Michael L Fitzgerald
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Explore the profile of Michael L Fitzgerald including associated specialties, affiliations and a list of published articles.
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46
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2564
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Recent Articles
11.
Toribio M, Park M, Zanni M, Robbins G, Burdo T, Williams K, et al.
J Clin Endocrinol Metab
. 2017 Sep;
102(11):4250-4259.
PMID: 28945911
Context: In the general population, high-density lipoprotein (HDL) cholesterol efflux capacity (HCEC) relates inversely to incident cardiovascular events. Previous studies have suggested that HCEC is decreased in HIV and that...
12.
Nowyhed H, Chandra S, Kiosses W, Marcovecchio P, Andary F, Zhao M, et al.
Sci Rep
. 2017 Jan;
7:40273.
PMID: 28091533
ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to the exocytoplasmic leaflet of membranes. Invariant NKT (iNKT) cells are a...
13.
Zimmer S, Grebe A, Bakke S, Bode N, Halvorsen B, Ulas T, et al.
Sci Transl Med
. 2016 Apr;
8(333):333ra50.
PMID: 27053774
Atherosclerosis is an inflammatory disease linked to elevated blood cholesterol concentrations. Despite ongoing advances in the prevention and treatment of atherosclerosis, cardiovascular disease remains the leading cause of death worldwide....
14.
Sakae N, Liu C, Shinohara M, Frisch-Daiello J, Ma L, Yamazaki Y, et al.
J Neurosci
. 2016 Apr;
36(13):3848-59.
PMID: 27030769
Significance Statement: Gene variants inABCA7encoding ATP-binding cassette transporter A7 are associated with the increased risk for late-onset Alzheimer's disease (AD). Importantly, we found the altered brain lipid profile and impaired...
15.
Tamehiro N, Park M, Hawxhurst V, Nagpal K, Adams M, Zannis V, et al.
Biochemistry
. 2015 Oct;
54(46):6931-41.
PMID: 26506427
Macrophage ABCA1 effluxes lipid and has anti-inflammatory activity. The syntrophins, which are cytoplasmic PDZ protein scaffolding factors, can bind ABCA1 and modulate its activity. However, many of the data assessing...
16.
Siegel M, Borkowska A, Dubrovsky L, Roth M, Welti R, Roberts A, et al.
Atherosclerosis
. 2015 Sep;
243(1):19-29.
PMID: 26343868
Background And Aims: Coronary artery disease is a growing clinical problem in HIV-infected subjects. The increased risk of coronary events in this population has been linked to low levels of...
17.
Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj D, et al.
J Pharmacol Exp Ther
. 2015 Jul;
354(3):376-83.
PMID: 26126533
Previous studies demonstrated that liver X receptor (LXR) agonists inhibit human immunodeficiency virus (HIV) replication by upregulating cholesterol transporter ATP-binding cassette A1 (ABCA1), suppressing HIV production, and reducing infectivity of...
18.
Midtbo L, Borkowska A, Bernhard A, Ronnevik A, Lock E, Fitzgerald M, et al.
J Nutr Biochem
. 2015 Mar;
26(6):585-95.
PMID: 25776459
Introduction of vegetable ingredients in fish feed has affected the fatty acid composition in farmed Atlantic salmon (Salmo salar L). Here we investigated how changes in fish feed affected the...
19.
Lo J, Rosenberg E, Fitzgerald M, Bazner S, Ihenachor E, Hawxhurst V, et al.
Open Forum Infect Dis
. 2015 Mar;
1(3):ofu108.
PMID: 25734176
Background: Individuals infected with human immunodeficiency virus (HIV) have decreased high-density lipoprotein (HDL)-cholesterol and increased cardiovascular disease (CVD). Reverse cholesterol transport from macrophages may be inhibited by HIV and contribute...
20.
Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald M, Sviridov D, et al.
J Biol Chem
. 2014 Aug;
289(42):28870-84.
PMID: 25170080
HIV-infected patients are at increased risk of developing atherosclerosis, in part due to an altered high density lipoprotein profile exacerbated by down-modulation and impairment of ATP-binding cassette transporter A1 (ABCA1)...