Michael J O Wakelam
Overview
Explore the profile of Michael J O Wakelam including associated specialties, affiliations and a list of published articles.
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84
Citations
4931
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Recent Articles
1.
Sousa B, Klein Z, Taylor D, West G, Neo Huipeng A, Wakelam M, et al.
Rapid Commun Mass Spectrom
. 2023 Jan;
:e9472.
PMID: 36652341
Rationale: The present work shows comprehensive chromatographic methods and MS conditions that have been developed based on the chemical properties of each lipid subclass to detect low-abundance molecular species. This...
2.
Kochaj R, Martelletti E, Ingham N, Buniello A, Sousa B, Wakelam M, et al.
Cells
. 2022 Oct;
11(20).
PMID: 36291074
Peroxisome biogenesis disorders (due to gene mutations) are associated with symptoms that range in severity and can lead to early childhood death, but a common feature is hearing impairment. In...
3.
Chauve L, Hodge F, Murdoch S, Masoudzadeh F, Mann H, Lopez-Clavijo A, et al.
PLoS Biol
. 2021 Nov;
19(11):e3001431.
PMID: 34723964
To survive elevated temperatures, ectotherms adjust the fluidity of membranes by fine-tuning lipid desaturation levels in a process previously described to be cell autonomous. We have discovered that, in Caenorhabditis...
4.
Kofeler H, Eichmann T, Ahrends R, Bowden J, Danne-Rasche N, Dennis E, et al.
Nat Commun
. 2021 Aug;
12(1):4771.
PMID: 34362906
No abstract available.
5.
Di Carlo C, Sousa B, Manfredi M, Brandi J, Dalla Pozza E, Marengo E, et al.
Sci Rep
. 2021 Jun;
11(1):13297.
PMID: 34168259
Pancreatic cancer stem cells (PCSCs) play a key role in the aggressiveness of pancreatic ductal adenocarcinomas (PDAC); however, little is known about their signaling and metabolic pathways. Here we show...
6.
Gaud C, Sousa B, Nguyen A, Fedorova M, Ni Z, ODonnell V, et al.
F1000Res
. 2021 Jun;
10:4.
PMID: 33564392
Lipidomics increasingly describes the quantification using mass spectrometry of all lipids present in a biological sample. As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple...
7.
ODonnell V, Thomas D, Stanton R, Maillard J, Murphy R, Jones S, et al.
Function (Oxf)
. 2020 Nov;
1(1):zqaa002.
PMID: 33215159
Emerging studies increasingly demonstrate the importance of the throat and salivary glands as sites of virus replication and transmission in early COVID-19 disease. SARS-CoV-2 is an enveloped virus, characterized by...
8.
ODonnell V, FitzGerald G, Murphy R, Liebisch G, Dennis E, Quehenberger O, et al.
Circ Genom Precis Med
. 2020 Nov;
13(6):e003019.
PMID: 33196315
No abstract available.
9.
Liebisch G, Fahy E, Aoki J, Dennis E, Durand T, Ejsing C, et al.
J Lipid Res
. 2020 Oct;
61(12):1539-1555.
PMID: 33037133
A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS...
10.
Marshall J, Courage E, Elliott R, Fitzpatrick M, Kim A, Lopez-Clavijo A, et al.
PLoS One
. 2020 May;
15(5):e0233180.
PMID: 32437392
Lipoprotein lipase (LPL) is upregulated in atherosclerotic lesions and it may promote the progression of atherosclerosis, but the mechanisms behind this process are not completely understood. We previously showed that...