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Michael J MacDonald

Explore the profile of Michael J MacDonald including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 1734
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Recent Articles
1.
Fletcher L, Levitan A, McBride E, Kim J, Alves E, Aquila A, et al.
Sci Rep . 2024 Jul; 14(1):17283. PMID: 39068229
We report time resolved observations of the crystallization from liquid hydrogen, supercooled to temperatures below the melting point, using 11.2 keV X-ray diffraction from the Linac Coherent Light Source (LCLS)....
2.
MacDonald M, Ansari I, Riedemann A, Stoker S, Eickhoff J, Chlebeck P, et al.
Diabetes . 2022 Jun; 71(9):2058-2063. PMID: 35713886
Net synthesis of pancreatic β-cells peaks before 2 years of life. β-Cell mass is set within the first 5 years of life. In-frame translational readthrough of the NRP1 gene exon...
3.
Hatfield P, Gaffney J, Anderson G, Ali S, Antonelli L, Basegmez du Pree S, et al.
Nature . 2021 May; 593(7859):351-361. PMID: 34012079
High-energy-density physics is the field of physics concerned with studying matter at extremely high temperatures and densities. Such conditions produce highly nonlinear plasmas, in which several phenomena that can normally...
4.
MacDonald M, Ansari I, Longacre M, Stoker S
Diabetes . 2021 Apr; 70(7):1575-1580. PMID: 33849997
Mitochondrial glycerol phosphate dehydrogenase (mGPD) is the rate-limiting enzyme of the glycerol phosphate redox shuttle. It was recently claimed that metformin, a first-line drug used for the treatment of type...
5.
Albertson L, MacDonald M, Tumolo B, Briggs M, Maguire Z, Quinn S, et al.
Ecol Lett . 2020 Dec; 24(3):594-607. PMID: 33368953
Positive interactions are sensitive to human activities, necessitating synthetic approaches to elucidate broad patterns and predict future changes if these interactions are altered or lost. General understanding of freshwater positive...
6.
Tumolo B, Calle L, Anderson H, Briggs M, Carlson S, MacDonald M, et al.
Ecol Evol . 2020 Sep; 10(17):9026-9036. PMID: 32953043
Given unprecedented rates of biodiversity loss, there is an urgency to better understand the ecological consequences of interactions among organisms that may lost or altered. Positive interactions among organisms of...
7.
Kritcher A, Swift D, Doppner T, Bachmann B, Benedict L, Collins G, et al.
Nature . 2020 Aug; 584(7819):51-54. PMID: 32760045
White dwarfs represent the final state of evolution for most stars. Certain classes of white dwarfs pulsate, leading to observable brightness variations, and analysis of these variations with theoretical stellar...
8.
Wattanavanitchakorn S, Ansari I, El Azzouny M, Longacre M, Stoker S, MacDonald M, et al.
Arch Biochem Biophys . 2019 Oct; 676:108124. PMID: 31585072
Pyruvate carboxylase (PC) is an anaplerotic enzyme that supplies oxaloacetate to mitochondria enabling the maintenance of other metabolic intermediates consumed by cataplerosis. Using liquid chromatography mass spectrometry (LC-MS) to measure...
9.
Wattanavanitchakorn S, Rojvirat P, Chavalit T, MacDonald M, Jitrapakdee S
PLoS One . 2018 Mar; 13(3):e0194252. PMID: 29566023
Fructose-1,6-bisphosphatase (FBP1) plays an essential role in gluconeogenesis. Here we report that the human FBP1 gene is regulated by two liver-enriched transcription factors, CCAAT-enhancer binding protein-α (C/EBPα) and hepatocyte nuclear...
10.
Ansari I, Longacre M, Stoker S, Kendrick M, ONeill L, Zitur L, et al.
Arch Biochem Biophys . 2017 Feb; 618:32-43. PMID: 28193492
Long-chain acyl-CoA synthetases (ACSLs) convert fatty acids to fatty acyl-CoAs to regulate various physiologic processes. We characterized the ACSL isoforms in a cell line of homogeneous rat beta cells (INS-1...