Michael J Duggan
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Explore the profile of Michael J Duggan including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
210
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Recent Articles
1.
Pham Q, Hwabejire J, Elsharkawy A, Eid A, Duggan M, Gelsinger S, et al.
Trauma Surg Acute Care Open
. 2025 Feb;
10(1):e001701.
PMID: 39963313
Background: Mortality for patients with pelvic fracture with hemorrhagic shock ranges from 21% to 57%. ResQFoam administered intra-abdominally has previously been shown to provide a survival benefit in large-animal models...
2.
Lagazzi E, Wei H, Panossian V, Pallotta J, Calisir A, Rafaqat W, et al.
Eur J Trauma Emerg Surg
. 2024 May;
50(4):1891-1901.
PMID: 38780780
Purpose: Noncompressible truncal hemorrhage remains a leading cause of preventable death in the prehospital setting. Standardized and reproducible large animal models are essential to test new therapeutic strategies. However, existing...
3.
Dorken-Gallastegi A, Naar L, Argandykov D, Lagazzi E, Dowling M, Montero P, et al.
Surgery
. 2023 Dec;
175(4):1189-1197.
PMID: 38092635
Background: A novel hydrophobically modified chitosan (hm-chitosan) polymer has been previously shown to improve survival in a non-compressible intra-abdominal bleeding model in swine. We performed a 28-day survival study to...
4.
King D, Hwabejire J, Pham Q, Elsharkawy A, Eid A, Duggan M, et al.
J Trauma Acute Care Surg
. 2023 Sep;
96(5):727-734.
PMID: 37700445
Background: Mortality for pelvic fracture patients presenting with hemorrhagic shock ranges from 21% to 57%. The objective of this study was to develop a lethal and clinically relevant pelvic hemorrhage...
5.
Naar L, Dorken Gallastegi A, Dowling M, Mashbari H, Wallace B, Bankhead-Kendall B, et al.
Surgery
. 2022 Feb;
172(1):421-426.
PMID: 35184891
Background: In military combat settings, noncompressible closed cavity exsanguination is the leading cause of potentially survivable deaths, with no effective treatment available at point of injury. The aim of this...
6.
Dowling M, MacIntire I, White J, Narayan M, Duggan M, King D, et al.
ACS Biomater Sci Eng
. 2021 Jan;
1(6):440-447.
PMID: 33445247
Hemorrhage (severe blood loss) from traumatic injury is a leading cause of death for soldiers in combat and for young civilians. In some cases, hemorrhage can be stopped by applying...
7.
Nikolian V, Pan B, Mesar T, Dennahy I, Georgoff P, Duan X, et al.
Inflammation
. 2017 May;
40(4):1264-1274.
PMID: 28493077
Hemorrhage is a common cause of death in the battlefield. Valproic acid (VPA) has been associated with improved outcomes in multiple models of trauma, when combined with isotonic fluid resuscitation....
8.
Avery R, Albadawi H, Akbari M, Zhang Y, Duggan M, Sahani D, et al.
Sci Transl Med
. 2016 Nov;
8(365):365ra156.
PMID: 27856795
Improved endovascular embolization of vascular conditions can generate better patient outcomes and minimize the need for repeat procedures. However, many embolic materials, such as metallic coils or liquid embolic agents,...
9.
Su Z, Oto J, Wang J, Kimball W, Chenelle C, Kacmarek R, et al.
Comp Med
. 2015 Jul;
65(3):225-31.
PMID: 26141447
Measuring tidal volume (VT) in nonintubated swine or swine with leaking breathing circuits is challenging. The aim of this study was to validate respiratory inductance plethysmography (RIP) for measuring VT...
10.
Rago A, Duggan M, Hannett P, Brennecke L, LaRochelle A, Khatri C, et al.
J Trauma Acute Care Surg
. 2015 Jul;
79(4 Suppl 2):S78-84.
PMID: 26131784
Background: Noncompressible hemorrhage is a significant cause of preventable death in trauma, with no effective presurgical treatments. We previously described the efficacy and 28-day safety of a self-expanding hemostatic foam...