Michael J Booth
Overview
Explore the profile of Michael J Booth including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
1277
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Recent Articles
1.
Kashyap D, Booth M
ACS Bio Med Chem Au
. 2025 Feb;
5(1):3-15.
PMID: 39990950
Nucleic acids have emerged as a powerful class of therapeutics. Through simple base pair complementarity, nucleic acids allow the targeting of a variety of pathologically relevant proteins and RNA molecules....
2.
3.
Chung K, Booth M
Chem Sci
. 2023 Nov;
14(44):12693-12706.
PMID: 38020373
Plasmids are ubiquitous in biology, where they are used to study gene-function relationships and intricate molecular networks, and hold potential as therapeutic devices. Developing methods to control their function will...
4.
Smith J, Hartmann D, Booth M
Nat Chem Biol
. 2023 Jul;
19(9):1138-1146.
PMID: 37414974
Gene-expressing compartments assembled from simple, modular parts, are a versatile platform for creating minimal synthetic cells with life-like functions. By incorporating gene regulatory motifs into their encapsulated DNA templates, in...
5.
Hartmann D, Chowdhry R, Smith J, Booth M
J Am Chem Soc
. 2023 May;
145(17):9471-9480.
PMID: 37125650
Cell-free gene expression is a vital research tool to study biological systems in defined minimal environments and has promising applications in biotechnology. Developing methods to control DNA templates for cell-free...
6.
Mazzotti G, Hartmann D, Booth M
J Am Chem Soc
. 2023 Apr;
145(17):9481-9487.
PMID: 37074404
Cell-free expression of a gene to protein has become a vital tool in nanotechnology and synthetic biology. Remote-control of cell-free systems with multiple, orthogonal wavelengths of light would enable precise,...
7.
Hartmann D, Booth M
Chem Commun (Camb)
. 2023 Apr;
59(38):5685-5688.
PMID: 37073467
Developing simple methods to silence antisense oligonucleotides (ASOs) using photocages opens up the possibility of precise regulation of biological systems. Here, we have developed a photocaging strategy based on 'handcuffing'...
8.
Hartmann D, Booth M
Commun Chem
. 2023 Apr;
6(1):59.
PMID: 37005479
Controlling cell-free expression of a gene to protein with non-invasive stimuli is vital to the future application of DNA nanodevices and synthetic cells. However, little emphasis has been placed on...
9.
Leathers A, Walczak M, Brady R, Al Samad A, Kotar J, Booth M, et al.
J Am Chem Soc
. 2022 Sep;
144(38):17468-17476.
PMID: 36103297
Biological cells display complex internal architectures with distinct micro environments that establish the chemical heterogeneity needed to sustain cellular functions. The continued efforts to create advanced cell mimics, namely, artificial...
10.
Smith J, Chowdhry R, Booth M
Front Mol Biosci
. 2022 Jan;
8:809945.
PMID: 35071327
Synthetic cells, which mimic cellular function within a minimal compartment, are finding wide application, for instance in studying cellular communication and as delivery devices to living cells. However, to fully...