Michael C Berndt
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Explore the profile of Michael C Berndt including associated specialties, affiliations and a list of published articles.
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98
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2318
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Recent Articles
1.
Arce N, Cao W, Brown A, Legan E, Wilson M, Xu E, et al.
Nat Commun
. 2021 Apr;
12(1):2360.
PMID: 33883551
Von Willebrand factor (VWF) activates in response to shear flow to initiate hemostasis, while aberrant activation could lead to thrombosis. Above a critical shear force, the A1 domain of VWF...
2.
Wang Y, Chen W, Zhang W, Lee-Sundlov M, Casari C, Berndt M, et al.
Haematologica
. 2020 Jan;
106(1):220-229.
PMID: 31974202
During infection neuraminidase desialylates platelets and induces their rapid clearance from circulation. The underlying molecular basis, particularly the role of platelet glycoprotein (GP)Ibα therein, is not clear. Utilizing genetically altered...
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Razak N, Jones G, Bhandari M, Berndt M, Metharom P
Cancers (Basel)
. 2018 Oct;
10(10).
PMID: 30314362
Cancer-associated thrombosis is a major cause of mortality in cancer patients, the most common type being venous thromboembolism (VTE). Several risk factors for developing VTE also coexist with cancer patients,...
6.
Elaskalani O, Falasca M, Moran N, Berndt M, Metharom P
Cancers (Basel)
. 2017 Oct;
9(10).
PMID: 29064388
Platelets have been demonstrated to be vital in cancer epithelial-mesenchymal transition (EMT), an important step in metastasis. Markers of EMT are associated with chemotherapy resistance. However, the association between the...
7.
Schoenwaelder S, Darbousset R, Cranmer S, Ramshaw H, Orive S, Sturgeon S, et al.
Nat Commun
. 2017 Aug;
8:16125.
PMID: 28853434
This corrects the article DOI: 10.1038/ncomms12862.
8.
Elaskalani O, Berndt M, Falasca M, Metharom P
Cancers (Basel)
. 2017 Jul;
9(7).
PMID: 28737696
The majority of cancer-associated mortality results from the ability of tumour cells to metastasise leading to multifunctional organ failure and death. Disseminated tumour cells in the blood circulation are faced...
9.
Deng W, Xu Y, Chen W, Paul D, Syed A, Dragovich M, et al.
Nat Commun
. 2016 Sep;
7:12863.
PMID: 27670775
Mechanisms by which blood cells sense shear stress are poorly characterized. In platelets, glycoprotein (GP)Ib-IX receptor complex has been long suggested to be a shear sensor and receptor. Recently, a...
10.
Schoenwaelder S, Darbousset R, Cranmer S, Ramshaw H, Orive S, Sturgeon S, et al.
Nat Commun
. 2016 Sep;
7:12862.
PMID: 27670677
The 14-3-3 family of adaptor proteins regulate diverse cellular functions including cell proliferation, metabolism, adhesion and apoptosis. Platelets express numerous 14-3-3 isoforms, including 14-3-3ζ, which has previously been implicated in...