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Michael A Resnick

Explore the profile of Michael A Resnick including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Gladwell W, Yost O, Li H, Bell W, Chen S, Ward J, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38069117
Identifying and understanding genetic factors that influence the propagation of the human respiratory syncytial virus (RSV) can lead to health benefits and possibly augment recent vaccine approaches. We previously identified...
2.
Menendez D, Anand J, Murphy C, Bell W, Fu J, Slepushkina N, et al.
Oncotarget . 2022 Feb; 13:332-346. PMID: 35178190
The functional status of the tumor suppressor p53 is a critical component in determining the sensitivity of cancer cells to many chemotherapeutic agents. DNA topoisomerase II (Top2) plays essential roles...
3.
Menendez D, Snipe J, Marzec J, Innes C, Polack F, Caballero M, et al.
J Clin Invest . 2019 Aug; 129(11):4875-4884. PMID: 31430261
The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 expression was increased...
4.
Nguyen T, Grimm S, Bushel P, Li J, Li Y, Bennett B, et al.
Nucleic Acids Res . 2018 Aug; 46(16):8153-8167. PMID: 30107566
p53 transcriptional networks are well-characterized in many organisms. However, a global understanding of requirements for in vivo p53 interactions with DNA and relationships with transcription across human biological systems in...
5.
Alessandrini F, Pezze L, Menendez D, Resnick M, Ciribilli Y
Neoplasia . 2018 Jul; 20(8):857-870. PMID: 30025229
Breast cancer treatment often includes Doxorubicin as adjuvant as well as neoadjuvant chemotherapy. Despite its cytotoxicity, cells can develop drug resistance to Doxorubicin. Uncovering pathways and mechanisms involved in drug...
6.
Westmoreland J, Mihalevic M, Bernstein K, Resnick M
DNA Repair (Amst) . 2017 Dec; 62:8-17. PMID: 29247743
Yeast Cdc13 protein (related to human CTC1) maintains telomere stability by preventing 5'-3' end resection. While Cdc13 and Yku70/Yku80 proteins appear to prevent excessive resection, their combined contribution to maintenance...
7.
Sagi D, Marcos-Hadad E, Bari V, Resnick M, Covo S
G3 (Bethesda) . 2017 Oct; 7(10):3305-3315. PMID: 28983067
Loss of heterozygosity (LOH) is an important factor in cancer, pathogenic fungi, and adaptation to changing environments. The sister chromatid cohesion process (SCC) suppresses aneuploidy and therefore whole chromosome LOH....
8.
Menendez D, Nguyen T, Snipe J, Resnick M
Mol Cancer Res . 2017 Feb; 15(6):735-743. PMID: 28232385
The APOBEC3 (A3) family of proteins are DNA cytidine deaminases that act as sentinels in the innate immune response against retroviral infections and are responsive to IFN. Recently, a few...
9.
Lowe J, Nguyen T, Grimm S, Gabor K, Peddada S, Li L, et al.
Cell Death Differ . 2016 Nov; 24(1):181-191. PMID: 27834950
Tumor necrosis factor-α-induced protein 8 (TNFAIP8) is a stress-response gene that has been associated with cancer, but no studies have differentiated among or defined the regulation or function of any...
10.
Menendez D, Lowe J, Snipe J, Resnick M
Oncotarget . 2016 Aug; 7(38):61630-61642. PMID: 27533082
Diversity within the p53 transcriptional network can arise from a matrix of changes that include target response element sequences and p53 expression level variations. We previously found that wild type...