Michael A Resnick
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Explore the profile of Michael A Resnick including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Godin S, Zhang Z, Herken B, Westmoreland J, Lee A, Mihalevic M, et al.
Nucleic Acids Res
. 2016 Jun;
44(17):8199-215.
PMID: 27298254
Here, we investigate the role of the budding yeast Shu complex in promoting homologous recombination (HR) upon replication fork damage. We recently found that the Shu complex stimulates Rad51 filament...
12.
Westmoreland J, Resnick M
Nucleic Acids Res
. 2015 Oct;
44(2):695-704.
PMID: 26503252
Recombinational repair provides accurate chromosomal restitution after double-strand break (DSB) induction. While all DSB recombination repair models include 5'-3' resection, there are no studies that directly assess the resection needed...
13.
Shatz M, Shats I, Menendez D, Resnick M
Oncotarget
. 2015 Jul;
6(19):16963-80.
PMID: 26220208
The p53 tumor suppressor regulates transcription of genes associated with diverse cellular functions including apoptosis, growth arrest, DNA repair and differentiation. Recently, we established that p53 can modulate expression of...
14.
Sharma V, Jordan J, Ciribilli Y, Resnick M, Bisio A, Inga A
PLoS One
. 2015 Jul;
10(7):e0130170.
PMID: 26147604
The NF-κB transcription factor family plays a central role in innate immunity and inflammation processes and is frequently dysregulated in cancer. We developed an NF-κB functional assay in yeast to...
15.
Andres S, Appel C, Westmoreland J, Williams J, Nguyen Y, Robertson P, et al.
Nat Struct Mol Biol
. 2015 Jan;
22(2):158-66.
PMID: 25580577
Ctp1 (also known as CtIP or Sae2) collaborates with Mre11-Rad50-Nbs1 to initiate repair of DNA double-strand breaks (DSBs), but its functions remain enigmatic. We report that tetrameric Schizosaccharomyces pombe Ctp1...
16.
Covo S, Chiou E, Gordenin D, Resnick M
PLoS One
. 2015 Jan;
9(12):e113435.
PMID: 25551702
Sister chromatid cohesion (SCC), which is established during DNA replication, ensures genome stability. Establishment of SCC is inhibited in G2. However, this inhibition is relived and SCC is established as...
17.
Sakofsky C, Roberts S, Malc E, Mieczkowski P, Resnick M, Gordenin D, et al.
Cell Rep
. 2014 Jun;
7(5):1640-1648.
PMID: 24882007
Clusters of simultaneous multiple mutations can be a source of rapid change during carcinogenesis and evolution. Such mutation clusters have been recently shown to originate from DNA damage within long...
18.
Lowe J, Menendez D, Bushel P, Shatz M, Kirk E, Troester M, et al.
Cancer Res
. 2014 Apr;
74(8):2182-92.
PMID: 24737129
Macrophages are sentinel immune cells that survey the tissue microenvironment, releasing cytokines in response to both exogenous insults and endogenous events such as tumorigenesis. Macrophages mediate tumor surveillance and therapy-induced...
19.
Nguyen T, Menendez D, Resnick M, Anderson C
Hum Mutat
. 2014 Jan;
35(6):738-55.
PMID: 24395704
The wild-type (WT) human p53 (TP53) tumor suppressor can be posttranslationally modified at over 60 of its 393 residues. These modifications contribute to changes in TP53 stability and in its...
20.
Covo S, Puccia C, Argueso J, Gordenin D, Resnick M
Genetics
. 2013 Dec;
196(2):373-84.
PMID: 24298060
Gain or loss of chromosomes resulting in aneuploidy can be important factors in cancer and adaptive evolution. Although chromosome gain is a frequent event in eukaryotes, there is limited information...