Michael A Quezada
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Explore the profile of Michael A Quezada including associated specialties, affiliations and a list of published articles.
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6
Citations
176
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Recent Articles
1.
Barron T, Yalcin B, Su M, Byun Y, Gavish A, Shamardani K, et al.
Nature
. 2025 Feb;
PMID: 39972132
High-grade gliomas (HGGs) are the leading cause of brain cancer-related death. HGGs include clinically, anatomically and molecularly distinct subtypes that stratify into diffuse midline gliomas (DMGs), such as H3K27M-altered diffuse...
2.
Liu I, Cruzeiro G, Bjerke L, Rogers R, Grabovska Y, Beck A, et al.
Cancer Cell
. 2024 Sep;
PMID: 39232581
Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are lethal brain tumors lacking targeted therapies. They originate from interneuronal precursors; however, leveraging this origin for therapeutic insights remains unexplored. Here, we delineate a...
3.
Bredel M, Espinosa L, Kim H, Scholtens D, McElroy J, Rajbhandari R, et al.
Cell Rep Med
. 2023 Jun;
4(6):101082.
PMID: 37343523
Genetic alterations help predict the clinical behavior of diffuse gliomas, but some variability remains uncorrelated. Here, we demonstrate that haploinsufficient deletions of chromatin-bound tumor suppressor NFKB inhibitor alpha (NFKBIA) display...
4.
Liu I, Jiang L, Samuelsson E, Marco Salas S, Beck A, Hack O, et al.
Nat Genet
. 2022 Dec;
54(12):1881-1894.
PMID: 36471067
Histone 3 lysine27-to-methionine (H3-K27M) mutations most frequently occur in diffuse midline gliomas (DMGs) of the childhood pons but are also increasingly recognized in adults. Their potential heterogeneity at different ages...
5.
Panditharatna E, Marques J, Wang T, Trissal M, Liu I, Jiang L, et al.
Cancer Discov
. 2022 Oct;
12(12):2880-2905.
PMID: 36305736
Significance: Epigenetic dysregulation is at the core of H3K27M-glioma tumorigenesis. Here, we identify the BRG1-BAF complex as a critical regulator of enhancer and transcription factor landscapes, which maintain H3K27M glioma...
6.
Cho K, Gillespie S, Kalogriopoulos N, Quezada M, Jacko M, Monje M, et al.
Elife
. 2022 Mar;
11.
PMID: 35311648
Technologies for detecting cell-cell contacts are powerful tools for studying a wide range of biological processes, from neuronal signaling to cancer-immune interactions within the tumor microenvironment. Here, we report TRACC...
7.
Nagaraja S, Quezada M, Gillespie S, Arzt M, Lennon J, Woo P, et al.
Mol Cell
. 2019 Oct;
76(6):965-980.e12.
PMID: 31588023
Development of effective targeted cancer therapies is fundamentally limited by our molecular understanding of disease pathogenesis. Diffuse intrinsic pontine glioma (DIPG) is a fatal malignancy of the childhood pons characterized...