Michael A Jakupec
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Explore the profile of Michael A Jakupec including associated specialties, affiliations and a list of published articles.
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165
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2131
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Recent Articles
1.
Georg M, Legin A, Hejl M, Jakupec M, Becker J, Gottlich R
Chembiochem
. 2024 Sep;
25(23):e202400519.
PMID: 39301577
We report the synthesis and characterization of two novel cisplatin- alkylating agents conjugates. Combining a platinum based cytostatic agent with a sterically demanding alkylating agent could potentially induce further DNA...
2.
Songoen W, Wenisch D, Jakupec M, Phanchai W, Sukkhaeng S, Brecker L, et al.
ACS Omega
. 2024 Aug;
9(31):33888-33899.
PMID: 39130579
Phytochemical investigation of Buch.-Ham (Moraceae) leaves led to the identification of three of the rarely found flavan-benzofuranes named artocarpinol C (), 3--artocarpinol C (), and artocarpinol D () along with...
3.
Getreuer P, Marretta L, Toyoglu E, Domotor O, Hejl M, Prado-Roller A, et al.
Dalton Trans
. 2024 Mar;
53(12):5567-5579.
PMID: 38426897
In this contribution we report the synthesis, characterization and anticancer activity of novel cyclometalated 4-phenylthiazole-derived ruthenium(II) (2a-e) and osmium(II) (3a-e) complexes. Formation and sufficient purity of the complexes were unambigiously...
4.
Brynzak-Schreiber E, Schogl E, Bapp C, Cseh K, Kopatz V, Jakupec M, et al.
Chemosphere
. 2024 Feb;
353:141463.
PMID: 38423146
Amidst the global plastic pollution crisis, the gastrointestinal tract serves as the primary entry point for daily exposure to micro- and nanoplastics. We investigated the complex dynamics between polystyrene micro-...
5.
Posa V, Federa A, Cseh K, Wenisch D, Spengler G, May N, et al.
Inorg Chem
. 2024 Jan;
63(5):2401-2417.
PMID: 38265361
As cancer cells exhibit an increased uptake of iron, targeting the interaction with iron has become a straightforward strategy in the fight against cancer. This work comprehensively characterizes the chemical...
6.
Maier T, Wutschitz J, Gajic N, Hejl M, Cseh K, Mai S, et al.
Dalton Trans
. 2023 Oct;
52(44):16326-16335.
PMID: 37855721
The reaction of (1,2)-(cyclohexane-1,2-diamine)dichloridoplatinum(II) with maleic acid unexpectedly resulted in the formation of an organometallic platinum(II) complex featuring a ,-coordinating ligand. Additionally, a small series of close derivatives with increasing...
7.
Cseh K, Berasaluce I, Fuchs V, Banc A, Schweikert A, Prado-Roller A, et al.
Pharmaceutics
. 2023 Jul;
15(7).
PMID: 37514061
The synthesis, characterization and biological activity of tungstenocenes with varying biologically active (,-), (,- and (,- chelates are described. Complexes were characterized by H and C NMR, elemental analysis, ESI-mass...
8.
Lerchbammer-Kreith Y, Hejl M, Sommerfeld N, Weng-Jiang X, Odunze U, Mellor R, et al.
Pharmaceuticals (Basel)
. 2023 Jul;
16(7).
PMID: 37513938
Quaternary ammonium palmitoyl glycol chitosan (GCPQ) has already shown beneficial drug delivery properties and has been studied as a carrier for anticancer agents. Consequently, we synthesised cytotoxic platinum(IV) conjugates of...
9.
Galanski M, Jakupec M, Keppler B
Curr Med Chem
. 2023 Jun;
30(36):4167.
PMID: 37340661
An article was published in the journal "Current Medicinal Chemistry," Volume 12, No. 18, 2005, pp: 2075-2094 [1]. The first author is requesting an alteration in the name. Details of...
10.
Liu X, Wenisch D, Dahlke P, Jordan P, Jakupec M, Kowol C, et al.
Eur J Med Chem
. 2023 Jun;
257:115515.
PMID: 37295160
In the last decades, inflammation has been recognized as being closely connected to cancer, and joint strategies encompassing chemotherapeutic and anti-inflammatory agents have been extensively studied. In this work, a...