Mi Seul Park
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Explore the profile of Mi Seul Park including associated specialties, affiliations and a list of published articles.
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10
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132
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Recent Articles
1.
Sim G, Kehling A, Park M, Divoky C, Zhang H, Malhotra N, et al.
bioRxiv
. 2023 Nov;
PMID: 37961191
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute (AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process establishes the seed, central, 3' supplementary, and tail regions...
2.
Sim G, Kehling A, Park M, Divoky C, Zhang H, Malhotra N, et al.
Sci Rep
. 2023 Nov;
13(1):19761.
PMID: 37957252
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute (AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process establishes the seed, central, 3' supplementary, and tail regions...
3.
Sim G, Kehling A, Park M, Secor J, Divoky C, Zhang H, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
119(51):e2214335119.
PMID: 36508664
MicroRNAs (miRNAs) are about 22-nucleotide (nt) noncoding RNAs forming the effector complexes with Argonaute (AGO) proteins to repress gene expression. Although tiny RNAs (tyRNAs) shorter than 19 nt have been...
4.
Park M, Sim G, Kehling A, Nakanishi K
Proc Natl Acad Sci U S A
. 2020 Oct;
117(46):28576-28578.
PMID: 33122430
RNA interfering is a eukaryote-specific gene silencing by 20∼23-nucleotide (nt) microRNAs and small interfering RNAs that recruit Argonaute proteins to complementary RNAs for degradation. In humans, Argonaute2 (AGO2) has been...
5.
Park M, Araya-Secchi R, Brackbill J, Phan H, Kehling A, Abd El-Wahab E, et al.
Mol Cell
. 2019 Jul;
75(4):725-740.e6.
PMID: 31324450
Despite the relevance of Argonaute proteins in RNA silencing, little is known about the structural steps of small RNA loading to form RNA-induced silencing complexes (RISCs). We report the 1.9 ...
6.
Park M, Phan H, Busch F, Hinckley S, Brackbill J, Wysocki V, et al.
Nucleic Acids Res
. 2017 Oct;
45(20):11867-11877.
PMID: 29040713
Of the four human Argonaute (AGO) paralogs, only AGO2 has been shown to have slicer activity. The others (AGO1, AGO3 and AGO4) have been thought to assemble with microRNAs to...
7.
Park S, Kim H, Park M, Moon S, Song M, Park H, et al.
PLoS One
. 2015 Dec;
10(12):e0145331.
PMID: 26709515
Thermoplasma acidophilum is a thermophilic archaeon that uses both non-phosphorylative Entner-Doudoroff (ED) pathway and Embden-Meyerhof-Parnas (EMP) pathway for glucose degradation. While triosephosphate isomerase (TPI), a well-known glycolytic enzyme, is not...
8.
Park M, Bitto E, Kim K, Bingman C, Miller M, Kim H, et al.
PLoS One
. 2014 Oct;
9(10):e111142.
PMID: 25356641
The N-end rule states that half-life of protein is determined by their N-terminal amino acid residue. N-terminal glutamine amidohydrolase (Ntaq) converts N-terminal glutamine to glutamate by eliminating the amine group...
9.
Kim K, Park S, Kim H, Rhee K, Kim B, Kim D, et al.
Proteins
. 2013 Apr;
81(10):1840-6.
PMID: 23609930
Human cytosolic aspartyl-tRNA synthetase (DRS) catalyzes the attachment of the amino acid aspartic acid to its cognate tRNA and it is a component of the multi-tRNA synthetase complex (MSC) which...
10.
Park S, Chung H, Kim D, Han M, Park M, Oh U, et al.
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2011 Nov;
67(Pt 10):1250-2.
PMID: 22102040
Transmembrane protein 16A (TMEM16A, also known as anoctamin 1; ANO1) is a bona fide Ca(2+)-activated chloride channel that is activated by intracellular Ca(2+)- and Ca(2+)-mobilizing stimuli and plays important roles...