Merritt P Edlind
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Explore the profile of Merritt P Edlind including associated specialties, affiliations and a list of published articles.
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6
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1012
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Recent Articles
1.
Hsieh A, Nguyen H, Wen L, Edlind M, Carroll P, Kim W, et al.
Sci Signal
. 2015 Nov;
8(403):ra116.
PMID: 26577921
Pharmacological inhibitors against the PI3K-AKT-mTOR (phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin) pathway, a frequently deregulated signaling pathway in cancer, are clinically promising, but the development of drug resistance is a major...
2.
Edlind M, Hsieh A
Asian J Androl
. 2014 Apr;
16(3):378-86.
PMID: 24759575
Prostate cancer (PCa) is the second most common malignancy among men in the world. Castration-resistant prostate cancer (CRPC) is the lethal form of the disease, which develops upon resistance to...
3.
Hsieh A, Liu Y, Edlind M, Ingolia N, Janes M, Sher A, et al.
Nature
. 2012 Feb;
485(7396):55-61.
PMID: 22367541
The mammalian target of rapamycin (mTOR) kinase is a master regulator of protein synthesis that couples nutrient sensing to cell growth and cancer. However, the downstream translationally regulated nodes of...
4.
Yuan Z, Edlind M, Liu P, Saenkham P, Banta L, Wise A, et al.
Proc Natl Acad Sci U S A
. 2007 Jul;
104(28):11790-5.
PMID: 17606909
Agrobacterium tumefaciens is capable of transferring and integrating an oncogenic T-DNA (transferred DNA) from its tumor-inducing (Ti) plasmid into dicotyledonous plants. This transfer requires that the virulence genes (vir regulon)...
5.
Edlind T, Henry K, Vermitsky J, Edlind M, Raj S, Katiyar S
Curr Genet
. 2005 Aug;
48(2):117-25.
PMID: 16078083
PCR product-based gene disruption has greatly accelerated molecular analysis of Saccharomyces cerevisiae. This approach involves amplification of a marker gene (e.g., URA3) including its flanking regulatory (promoter and polyadenylation) regions...
6.
Edlind M, Smith W, Edlind T
Antimicrob Agents Chemother
. 2005 Jan;
49(2):843-5.
PMID: 15673785
Mouthwash antiseptic cetylpyridinium chloride (CPC) has potent activity against Candida albicans; however, two of five azole-resistant strains showed reduced CPC susceptibility. To further examine the potential for cross-resistance, CPC-resistant mutants...