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Giulio Maria Pasinetti

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Articles 102
Citations 2655
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Recent Articles
1.
Iban-Arias R, Portela A, Masieri S, Radu A, Yang E, Chen L, et al.
Biochim Biophys Acta Mol Basis Dis . 2025 Mar; 1871(5):167760. PMID: 40037471
Climate change-induced environmental stressors, including ambient particulate matter (PM) and extreme heat stress (HS), pose serious health risks, particularly for neurodegenerative diseases. PM exacerbates cardiovascular and neurodegenerative conditions, while HS...
2.
Naughton S, Yang E, Iqbal U, Trageser K, Charytonowicz D, Masieri S, et al.
J Neuroinflammation . 2024 Sep; 21(1):222. PMID: 39272155
Gulf War Illness (GWI) is a chronic multisymptom disorder that affects approximately 25-32% of Gulf War veterans and is characterized by a number of symptoms such as cognitive impairment, psychiatric...
3.
Iban-Arias R, Wang S, Portela A, Yang E, Griggs E, Masieri S, et al.
J Alzheimers Dis . 2024 Aug; 100(s1):S305-S325. PMID: 39093074
Background: The September 11, 2001, catastrophe unleashed widespread destruction beyond the World Center (WTC), with fires and toxic gases leaving lasting impacts. First responders at Ground Zero faced prolonged exposure...
4.
Portela A, Iban-Arias R, Saxena V, Masieri S, Pasinetti G
Mol Nutr Food Res . 2024 Jul; 68(13):e2400381. PMID: 39031520
The acquisition of novel insights derived from the biological and genetic profiles of patients will pave the way for tailored interventions and guidance, facilitated by pioneering methodologies and investigations in...
5.
Granov R, Vedad S, Wang S, Durham A, Shah D, Pasinetti G
Mol Neurobiol . 2024 Jul; 62(1):1205-1224. PMID: 38967905
With the continuous increase of the elderly population, there is an urgency to understand and develop relevant treatments for Alzheimer's disease and related dementias (ADRD). In tandem with this, the...
6.
Iban-Arias R, Yang E, Griggs E, Portela A, Osman A, Trageser K, et al.
Brain Behav Immun . 2024 Mar; 118:252-272. PMID: 38461954
Immune system dysfunction is increasingly recognized as a significant feature that contributes to Alzheimer's disease (AD) pathogenesis, reflected by alterations in central and peripheral responses leading to detrimental mechanisms that...
7.
Portela A, Saxena V, Rosenn E, Wang S, Masieri S, Palmieri J, et al.
Mol Nutr Food Res . 2024 Jan; 68(13):e2300605. PMID: 38175857
Alzheimer's disease (AD) affects 50 million people worldwide, an increase of 35 million since 2015, and it is known for memory loss and cognitive decline. Considering the morbidity associated with...
8.
Yang E, Rahim M, Griggs E, Iban-Arias R, Pasinetti G
PNAS Nexus . 2023 Aug; 2(8):pgad251. PMID: 37614669
Forkhead box P3 (Foxp3) is a transcription factor that influences functioning of regulatory T cells (Tregs) that modulate peripheral immune response. Treg-mediated innate immunity and Treg-mediated adaptive immunity are receiving...
9.
Griggs E, Trageser K, Naughton S, Yang E, Mathew B, Van Hyfte G, et al.
Elife . 2023 Jul; 12. PMID: 37417740
Infection with the etiological agent of COVID-19, SARS-CoV-2, appears capable of impacting cognition in some patients with post-acute sequelae of SARS-CoV-2 (PASC). To evaluate neuropathophysiological consequences of SARS-CoV-2 infection, we...
10.
Trageser K, Yang E, Smith C, Iban-Arias R, Oguchi T, Sebastian-Valverde M, et al.
Mol Neurobiol . 2023 Apr; 60(7):4004-4016. PMID: 37010807
Intronic GC hexanucleotide repeat expansions (HRE) of C9orf72 are the most common cause of familial variants of frontotemporal dementia/amyotrophic lateral sclerosis (FTD/ALS). GC HREs in C9orf72 undergo non-canonical repeat-associated translation,...