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Melia Magnen

Explore the profile of Melia Magnen including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 458
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Recent Articles
1.
Conrad C, Magnen M, Tsui J, Wismer H, Naser M, Venkataramani U, et al.
Blood . 2025 Feb; PMID: 40014797
While the bone marrow is the main site of blood cell production in adults, rare pools of hematopoietic stem and progenitor cells have been found in extramedullary organs. In mice,...
2.
Moussavi-Harami S, Cleary S, Magnen M, Seo Y, Conrad C, English B, et al.
J Clin Invest . 2024 Oct; 134(24). PMID: 39352872
Acute respiratory distress syndrome (ARDS) is associated with significant morbidity and mortality, and neutrophils are critical to its pathogenesis. Neutrophil activation is closely regulated by inhibitory tyrosine phosphatases including Src...
3.
Magnen M, You R, Rao A, Davis R, Rodriguez L, Bernard O, et al.
Sci Adv . 2024 Jul; 10(31):eadm8836. PMID: 39083602
In the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, epithelial populations in the distal lung expressing Angiotensin-converting enzyme 2 (ACE2) are infrequent, and therefore, the model of...
4.
Estur F, Murigneux E, David A, Magnen M, Saidi A, Lalmanach G, et al.
Biochimie . 2024 Mar; 226:29-34. PMID: 38494107
A long-term exposure to cigarette smoke (CS) alters the integrity of airway epithelial barrier, contributes to lung dysfunction, and elicits the expression and activity of lung cathepsin S (CatS), a...
5.
Conrad C, Magnen M, Tsui J, Wismer H, Naser M, Venkataramani U, et al.
Res Sq . 2023 Dec; PMID: 38077002
The bone marrow is the main site of blood cell production in adults, however, rare pools of hematopoietic stem and progenitor cells with self-renewal and differentiation potential have been found...
6.
Seo Y, Qiu L, Magnen M, Conrad C, Moussavi-Harami S, Looney M, et al.
Am J Physiol Lung Cell Mol Physiol . 2023 Jul; 325(2):L262-L269. PMID: 37401383
Microbes, toxins, therapeutics, and cells are often instilled into lungs of mice to model diseases and test experimental interventions. Consistent pulmonary delivery is critical for experimental power and reproducibility, but...
7.
Sorrells M, Seo Y, Magnen M, Broussard B, Sheybani R, Shah A, et al.
Diagnostics (Basel) . 2023 May; 13(8). PMID: 37189536
Sepsis, the leading cause of mortality in hospitals, currently lacks effective early diagnostics. A new cellular host response test, the IntelliSep test, may provide an indicator of the immune dysregulation...
8.
Hysenaj L, Little S, Kulhanek K, Magnen M, Bahl K, Gbenedio O, et al.
Stem Cell Reports . 2023 Feb; 18(3):636-653. PMID: 36827975
Ancestral SARS coronavirus-2 (SARS-CoV-2) and variants of concern (VOC) caused a global pandemic with a spectrum of disease severity. The mechanistic explaining variations related to airway epithelium are relatively understudied....
9.
Seo Y, Qiu L, Magnen M, Conrad C, Moussavi-Harami S, Looney M, et al.
bioRxiv . 2023 Feb; PMID: 36778478
Microbes, toxins, therapeutics and cells are often instilled into lungs of mice to model diseases and test experimental interventions. Consistent pulmonary delivery is critical for experimental power and reproducibility, but...
10.
Calabrese D, Tsao T, Magnen M, Valet C, Gao Y, Mallavia B, et al.
JCI Insight . 2022 Nov; 7(24). PMID: 36346670
Clinical outcomes after lung transplantation, a life-saving therapy for patients with end-stage lung diseases, are limited by primary graft dysfunction (PGD). PGD is an early form of acute lung injury...