Mei-Juan Tu
Overview
Explore the profile of Mei-Juan Tu including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
930
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0
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Recent Articles
1.
Traber G, Tu M, Guan S, Batra N, Yu A
Mol Pharmacol
. 2025 Feb;
107(1):100006.
PMID: 39919164
Reintroduction of tumor-suppressive microRNA-7-5p (miR-7) that is depleted in non-small cell lung cancer (NSCLC) represents a new therapeutic approach, whereas previous studies mainly used miR-7 mimics chemoengineered in vitro. Here...
2.
Mao F, Tu M, Traber G, Yu A
Noncoding RNA
. 2024 Nov;
10(6.
PMID: 39585047
Understanding the structures of noncoding RNAs (ncRNAs) is important for the development of RNA-based therapeutics. There are inherent challenges in employing current experimental techniques to determine the tertiary (3D) structures...
3.
Wang Z, Tu M, Liu Z, Wang K, Fang Y, Hao N, et al.
bioRxiv
. 2024 Sep;
PMID: 39345479
Nucleotide modifications deviate nanopore sequencing readouts, therefore generating artifacts during the basecalling of sequence backbones. Here, we present an iterative approach to polish modification-disturbed basecalling results. We show such an...
4.
Wang Z, Tu M, Song C, Liu Z, Wang K, Chen S, et al.
bioRxiv
. 2024 Sep;
PMID: 39345391
The nanopore sequencing of short sequences, whose lengths are typically less than 0.3kb therefore comparable with Illumina sequencing techniques, has recently gained wide attention. Here, we design a scheme for...
5.
Wang Y, Tu M, Yu A
Front Pharmacol
. 2024 Aug;
15:1423416.
PMID: 39114355
ATP-binding cassette (ABC) transporters are transmembrane proteins expressed commonly in metabolic and excretory organs to control xenobiotic or endobiotic disposition and maintain their homeostasis. Changes in ABC transporter expression may...
6.
Batra N, Tu M, Yu A
ACS Synth Biol
. 2024 May;
13(6):1906-1915.
PMID: 38733599
Synthetic biology constitutes a scientific domain focused on intentional redesign of organisms to confer novel functionalities or create new products through strategic engineering of their genetic makeup. Leveraging the inherent...
7.
Traber G, Yi C, Batra N, Tu M, Yu A
RNA
. 2024 Mar;
30(6):680-694.
PMID: 38429100
Genome-derived microRNAs (miRNAs or miRs) govern posttranscriptional gene regulation and play important roles in various cellular processes and disease progression. While chemo-engineered miRNA mimics or biosimilars made in vitro are...
8.
Chen Y, Tu M, Han F, Liu Z, Batra N, Lara P, et al.
Acta Pharm Sin B
. 2023 Oct;
13(10):4273-4290.
PMID: 37799388
During the development of therapeutic microRNAs (miRNAs or miRs), it is essential to define their pharmacological actions. Rather, miRNA research and therapy mainly use miRNA mimics synthesized . After experimental...
9.
Deng L, Petrek H, Tu M, Batra N, Yu A, Yu A
Acta Pharm Sin B
. 2023 Sep;
13(8):3577-3578.
PMID: 37655312
[This corrects the article DOI: 10.1016/j.apsb.2021.07.027.].
10.
Tu M, Yu A
Curr Drug Metab
. 2023 May;
24(3):175-189.
PMID: 37170982
Drug-metabolizing enzymes and transporters are major determinants of the absorption, disposition, metabolism, and excretion (ADME) of drugs, and changes in ADME gene expression or function may alter the pharmacokinetics/ pharmacodynamics...