Pui Yan Ho
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Explore the profile of Pui Yan Ho including associated specialties, affiliations and a list of published articles.
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20
Citations
467
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Recent Articles
1.
Rodriguez L, Zamora J, Han D, Moshiri J, Peinovich N, Martinez C, et al.
Viruses
. 2025 Feb;
17(2).
PMID: 40006923
As new SARS-CoV-2 variants continue to emerge, it is important to evaluate the potency of antiviral drugs to support their continued use. Remdesivir (RDV; VEKLURY) an approved antiviral treatment for...
2.
Chan Y, Ho P, Dib C, Swartzrock L, Rayburn M, Willner H, et al.
Stem Cell Res Ther
. 2024 Oct;
15(1):387.
PMID: 39473008
Background: Hematopoietic stem cell transplantation (HSCT) is a curative treatment for many diverse blood and immune diseases. However, HSCT regimens currently commonly utilize genotoxic chemotherapy and/or total body irradiation (TBI)...
3.
Igarashi K, Kucinski I, Chan Y, Tan T, Khoo H, Kealy D, et al.
Blood Adv
. 2023 Feb;
7(14):3366-3377.
PMID: 36809781
Hematopoietic stem cells (HSCs) are a rare type of hematopoietic cell that can entirely reconstitute the blood and immune system after transplantation. Allogeneic HSC transplantation (HSCT) is used clinically as...
4.
Jing D, Jiang N, Wang F, Mao C, Han S, Ho P, et al.
Biomaterials
. 2022 Sep;
289:121769.
PMID: 36084485
Low dose non-toxic disulfide cross-linked micelle (DCM) encapsulated paclitaxel (PTX) was found to be highly efficacious as a radiosensitizer against oral cancer preclinical model. Intensity-modulated radiation therapy was locally administered...
5.
Chan Y, Ho P, Swartzrock L, Rayburn M, Nofal R, Thongthip S, et al.
Transplant Cell Ther
. 2022 Aug;
29(3):164.e1-164.e9.
PMID: 35995393
Hematopoietic stem cell transplantation (HSCT) is a curative treatment for patients with many different blood and immune diseases; however, current treatment regimens contain non-specific chemotherapy and/or irradiation conditioning, which carry...
6.
Ho P, Zhang Z, Hayes M, Curd A, Dib C, Rayburn M, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(45).
PMID: 34732575
Triplex gene editing relies on binding a stable peptide nucleic acid (PNA) sequence to a chromosomal target, which alters the helical structure of DNA to stimulate site-specific recombination with a...
7.
Li P, Tu M, Ho P, Batra N, Tran M, Qiu J, et al.
Theranostics
. 2021 Mar;
11(10):4858-4871.
PMID: 33754032
Noncoding RNAs (ncRNAs) such as microRNAs (miRs or miRNAs) play important roles in the control of cellular processes through posttranscriptional gene regulation. However, ncRNA research is limited to utilizing RNA...
8.
Petrek H, Ho P, Batra N, Tu M, Zhang Q, Qiu J, et al.
Biochem Pharmacol
. 2020 Dec;
189:114392.
PMID: 33359565
Lung cancer remains the leading cause of cancer deaths worldwide and accounts for more than 22% of all cancer-related deaths in the US. Developing new therapies is essential to combat...
9.
Carofino B, Dinshaw K, Ho P, Cataisson C, Michalowski A, Ryscavage A, et al.
Oncotarget
. 2020 Jan;
10(68):7251-7275.
PMID: 31921386
Chloride intracellular channel 4 (CLIC4) is a tumor suppressor implicated in processes including growth arrest, differentiation, and apoptosis. CLIC4 protein expression is diminished in the tumor parenchyma during progression in...
10.
Li X, Tian Y, Tu M, Ho P, Batra N, Yu A
Acta Pharm Sin B
. 2019 Jun;
9(3):639-647.
PMID: 31193825
Drug-metabolizing enzymes, transporters, and nuclear receptors are essential for the absorption, distribution, metabolism, and excretion (ADME) of drugs and xenobiotics. MicroRNAs participate in the regulation of ADME gene expression imperfect...