Md Ashraf-Uz-Zaman
Overview
Explore the profile of Md Ashraf-Uz-Zaman including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
45
Followers
0
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Recent Articles
1.
Ashraf-Uz-Zaman M, Chua T, Li X, Yao Y, Moku B, Mishra C, et al.
ACS Infect Dis
. 2024 Jan;
10(2):715-731.
PMID: 38192109
Highly contagious SARS-CoV-2 coronavirus has infected billions of people worldwide with flu-like symptoms since its emergence in 2019. It has caused deaths of several million people. The viral main protease...
2.
Li X, Wu X, Nie S, Zhao J, Yao Y, Wu F, et al.
Cancers (Basel)
. 2023 Nov;
15(21).
PMID: 37958457
Chromosomal translocations involving the mixed lineage leukemia (MLL) gene cause 5-10% acute leukemias with poor clinical outcomes. Protein-protein interactions (PPI) between the most frequent MLL fusion partner proteins AF9/ENL and...
3.
Ashraf-Uz-Zaman M, Li X, Yao Y, Mishra C, Moku B, Song Y
J Med Chem
. 2023 Jul;
66(15):10746-10760.
PMID: 37506506
Dengue (DENV) and Zika (ZIKV) viruses are important human pathogens, causing ∼100 million symptomatic infections each year. These infections carry a 20-fold increased incidence of serious neurological diseases, such as...
4.
Kumar N, Srivastava R, Mongre R, Mishra C, Kumar A, Khatoon R, et al.
Front Microbiol
. 2022 May;
13:818714.
PMID: 35602011
Mycolic acids are the key constituents of mycobacterial cell wall, which protect the bacteria from antibiotic susceptibility, helping to subvert and escape from the host immune system. Thus, the enzymes...
5.
Ashraf-Uz-Zaman M, Ji G, Tidwell D, Yin L, Thakolwiboon S, Pan J, et al.
ACS Chem Neurosci
. 2022 Jan;
13(2):217-228.
PMID: 34978174
The dopaminergic system is involved in the regulation of immune responses in various homeostatic and disease conditions. For conditions such as Parkinson's disease and multiple sclerosis (MS), pharmacological modulation of...
6.
Mongre R, Mishra C, Shukla A, Prakash A, Jung S, Ashraf-Uz-Zaman M, et al.
Int J Mol Sci
. 2021 Nov;
22(21).
PMID: 34769090
GLOBOCAN 2020 estimated more than 19.3 million new cases, and about 10 million patients were deceased from cancer in 2020. Clinical manifestations showed that several growth factor receptors consisting of...
7.
Ashraf-Uz-Zaman M, Shahi S, Akwii R, Sajib M, Jodeiri Farshbaf M, Kallem R, et al.
Eur J Med Chem
. 2020 Oct;
209:112866.
PMID: 33039722
Triple-negative breast cancer (TNBC) is an aggressive type of cancer characterized by higher metastatic and reoccurrence rates, where approximately one-third of TNBC patients suffer from the metastasis in the brain....
8.
Ashraf-Uz-Zaman M, Bhalerao A, Mikelis C, Cucullo L, German N
Cancers (Basel)
. 2020 May;
12(5).
PMID: 32429547
Chemoprevention of lung cancer is thought to significantly reduce the risk of acquiring these conditions in the subpopulation of patients with underlying health issues, such as chronic obstructive pulmonary disorder...
9.
Ashraf-Uz-Zaman M, Sajib M, Cucullo L, Mikelis C, German N
Bioorg Med Chem Lett
. 2018 Nov;
28(23-24):3652-3657.
PMID: 30389290
Several recent reports have highlighted the feasibility of the use of penfluridol, a well-known antipsychotic agent, as a chemotherapeutic agent. In vivo experiments have confirmed the cytotoxic activity of penfluridol...