Maya Umekita
Overview
Explore the profile of Maya Umekita including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
214
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Recent Articles
1.
Takehana Y, Muramatsu H, Hatano M, Ishizaki Y, Umekita M, Shibuya Y, et al.
J Antibiot (Tokyo)
. 2024 Oct;
78(1):14-25.
PMID: 39468287
A new bioactive substance was identified from a leaf-litter actinomycete strain by screening for antibacterial activity against Neisseria gonorrhoeae. The thiazolyl peptide antibiotic, named thiazoplanomicin, was isolated from the secondary...
2.
Yamasaki M, Sawa R, Muramatsu H, Yamamoto Y, Umekita M, Kubota Y, et al.
J Antibiot (Tokyo)
. 2023 Nov;
77(2):85-92.
PMID: 38008738
Hepatitis B virus (HBV) causes chronic hepatitis in humans, and current antiviral therapies rarely treat viral infections. To improve the treatment efficacy, novel therapeutic agents, especially those with different mechanisms...
3.
Ishizaki Y, Umekita M, Arisaka R, Hatano M, Kimura T, Kubota Y, et al.
J Antibiot (Tokyo)
. 2023 Sep;
76(12):691-698.
PMID: 37758819
Pseudomonas aeruginosa is one of the most concerning pathogenic bacteria. We screened antibiotics using a highly drug-sensitive P. aeruginosa strain and an oligotrophic medium, and successfully isolated novel antibiotics, namely...
4.
Kimura T, Umekita M, Hatano M, Hayashi C, Sawa R, Igarashi M
J Antibiot (Tokyo)
. 2022 Sep;
75(10):535-541.
PMID: 36071214
In the course of our screening program for new anti-methicillin-resistant Staphylococcus aureus antibiotics, four novel antibiotics, termed wychimicins A-D, were isolated from the culture broth of the rare actinomycete Actinocrispum...
5.
Takizawa N, Takada H, Umekita M, Igarashi M, Takahashi Y
Front Microbiol
. 2022 Mar;
13:802671.
PMID: 35250924
Seasonal influenza virus epidemics result in severe illness, and occasionally influenza pandemics cause significant morbidity and mortality, although vaccines and anti-influenza virus drugs are available. By screening an in-house library,...
6.
Kohda Y, Sakamoto S, Umekita M, Kimura T, Kubota Y, Arisaka R, et al.
J Antibiot (Tokyo)
. 2021 Dec;
75(2):77-85.
PMID: 34873311
New three macrocyclic diolides, named bispolides C-E (1-3), were isolated from a fermentation broth of the actinomycete strain MG372-hF19, which produces an indole glycoside and leptomycins as we reported previously....
7.
Takehana Y, Muramatsu H, Umekita M, Hayashi C, Kimura T, Sawa R, et al.
J Antibiot (Tokyo)
. 2021 Mar;
74(7):470-473.
PMID: 33758372
In the course of screening for new antimicrobial compounds, a new antibiotic substance named saccharobipyrimicin was isolated from the leaf-litter actinomycete Saccharothrix sp. MM696L-181F4. The structure of saccharobipyrimicin was elucidated...
8.
Igarashi M, Sawa R, Umekita M, Hatano M, Arisaka R, Hayashi C, et al.
J Antibiot (Tokyo)
. 2021 Feb;
74(5):291-299.
PMID: 33531630
A Nonomuraea sp. strain MM565M-173N2 was isolated from deep-sea sediment off the Sanriku coast, and new antibiotics were evaluated against carbapenem-resistant Enterobacteriaceae (CRE), which is a problematic group of bacteria...
9.
Yamasaki M, Igarashi M, Sawa R, Nosaka C, Umekita M, Hatano M, et al.
J Antibiot (Tokyo)
. 2019 Jan;
72(3):125-133.
PMID: 30622294
Influenza virus RNA polymerase has cap-dependent endonuclease activity that produces capped RNA fragments for priming viral mRNA synthesis. This enzymatic activity is essential for viral propagation, but it is not...
10.
Sawa R, Kubota Y, Umekita M, Hatano M, Hayashi C, Igarashi M
J Antibiot (Tokyo)
. 2017 Nov;
PMID: 29138481
Drug-resistant bacteria are still emerging, and screening of new skeletal antibiotics is important. During our continuous screening for antimicrobial agents, we discovered a new antimicrobial, named quadoctomycin, from solid culture...