Matthieu Chavent
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Explore the profile of Matthieu Chavent including associated specialties, affiliations and a list of published articles.
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40
Citations
940
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Recent Articles
11.
Spalvieri D, Mauviel A, Lambert M, Ferey N, Sacquin-Mora S, Chavent M, et al.
J Integr Bioinform
. 2022 Jul;
19(2).
PMID: 35776840
We discuss how design enriches molecular science, particularly structural biology and bioinformatics. We present two use cases, one in academic practice and the other to design for outreach. The first...
12.
The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X-small transmembrane motifs
Jackson V, Hermann J, Tynan C, Rolfe D, Corey R, Duncan A, et al.
Structure
. 2022 Jun;
30(9):1354-1365.e5.
PMID: 35700726
Fibronectin Leucine-rich Repeat Transmembrane (FLRT 1-3) proteins are a family of broadly expressed single-spanning transmembrane receptors that play key roles in development. Their extracellular domains mediate homotypic cell-cell adhesion and...
13.
Zivkovic D, Sanchez Dafun A, Menneteau T, Schahl A, Lise S, Kervarrec C, et al.
Proc Natl Acad Sci U S A
. 2022 Apr;
119(15):e2116826119.
PMID: 35377789
During spermatogenesis, spermatogonia undergo a series of mitotic and meiotic divisions on their path to spermatozoa. To achieve this, a succession of processes requiring high proteolytic activity are in part...
14.
Martinez X, Chavent M, Baaden M
Biochem Soc Trans
. 2020 Mar;
48(2):499-506.
PMID: 32196545
Molecular visualization is fundamental in the current scientific literature, textbooks and dissemination materials. It provides an essential support for presenting results, reasoning on and formulating hypotheses related to molecular structure....
15.
Del Toro D, Carrasquero-Ordaz M, Chu A, Ruff T, Shahin M, Jackson V, et al.
Cell
. 2020 Jan;
180(2):323-339.e19.
PMID: 31928845
Teneurins are ancient metazoan cell adhesion receptors that control brain development and neuronal wiring in higher animals. The extracellular C terminus binds the adhesion GPCR Latrophilin, forming a trans-cellular complex...
16.
Augenstreich J, Haanappel E, Ferre G, Czaplicki G, Jolibois F, Destainville N, et al.
Proc Natl Acad Sci U S A
. 2019 Nov;
116(51):25649-25658.
PMID: 31757855
Phthiocerol dimycocerosate (DIM) is a major virulence factor of the pathogen (). While this lipid promotes the entry of into macrophages, which occurs via phagocytosis, its molecular mechanism of action...
17.
Martinez X, Krone M, Alharbi N, Rose A, Laramee R, ODonoghue S, et al.
Structure
. 2019 Oct;
27(11):1617-1623.
PMID: 31564470
Visualization of molecular structures is one of the most common tasks carried out by structural biologists, typically using software, such as Chimera, COOT, PyMOL, or VMD. In this Perspective article,...
18.
Abraham M, Apostolov R, Barnoud J, Bauer P, Blau C, Bonvin A, et al.
J Chem Inf Model
. 2019 Sep;
59(10):4093-4099.
PMID: 31525920
Given the need for modern researchers to produce open, reproducible scientific output, the lack of standards and best practices for sharing data and workflows used to produce and analyze molecular...
19.
Hedger G, Koldso H, Chavent M, Siebold C, Rohatgi R, Sansom M
Structure
. 2019 Jan;
27(3):549-559.e2.
PMID: 30595453
Transduction of Hedgehog signals across the plasma membrane is facilitated by the class F G-protein-coupled-receptor (GPCR) Smoothened (SMO). Recent studies suggest that SMO is modulated via interactions of its transmembrane...
20.
Chavent M, Duncan A, Rassam P, Birkholz O, Helie J, Reddy T, et al.
Nat Commun
. 2018 Jul;
9(1):2846.
PMID: 30030429
The spatiotemporal organisation of membranes is often characterised by the formation of large protein clusters. In Escherichia coli, outer membrane protein (OMP) clustering leads to OMP islands, the formation of...