Tyler Reddy
Overview
Explore the profile of Tyler Reddy including associated specialties, affiliations and a list of published articles.
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24
Citations
8355
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Recent Articles
1.
Zhao M, Lopes L, Sahni H, Yadav A, Do H, Reddy T, et al.
J Phys Chem B
. 2024 Dec;
128(51):12710-12727.
PMID: 39670799
A fundamental understanding of how the HIV-1 envelope (Env) protein facilitates fusion is still lacking. The HIV-1 fusion peptide, consisting of 15 to 22 residues, is the N-terminus of the...
2.
Zhao M, Lopes L, Sahni H, Yadav A, Do H, Reddy T, et al.
bioRxiv
. 2024 Aug;
PMID: 39131401
A fundamental understanding of how HIV-1 envelope (Env) protein facilitates fusion is still lacking. The HIV-1 fusion peptide, consisting of 15 to 22 residues, is the N-terminus of the gp41...
3.
Nguyen K, Lopez C, Neale C, Van Q, Carpenter T, Di Natale F, et al.
Biophys J
. 2022 Jul;
121(19):3630-3650.
PMID: 35778842
During the activation of mitogen-activated protein kinase (MAPK) signaling, the RAS-binding domain (RBD) and cysteine-rich domain (CRD) of RAF bind to active RAS at the plasma membrane. The orientation of...
4.
Bryer A, Reddy T, Lyman E, Perilla J
PLoS Comput Biol
. 2022 Jan;
18(1):e1009781.
PMID: 35041642
Enveloped viruses are enclosed by a lipid membrane inside of which are all of the components necessary for the virus life cycle; viral proteins, the viral genome and metabolites. Viral...
5.
Gonzalez-Arias F, Reddy T, Stone J, Hadden-Perilla J, Perilla J
Comput Sci Eng
. 2021 Jan;
22(6):11-20.
PMID: 33510584
Enveloped viruses, such as SARS-CoV-2, infect cells via fusion of their envelope with the host membrane. By employing molecular simulations to characterize viral envelopes, researchers can gain insights into key...
6.
Harris C, Millman K, van der Walt S, Gommers R, Virtanen P, Cournapeau D, et al.
Nature
. 2020 Sep;
585(7825):357-362.
PMID: 32939066
Array programming provides a powerful, compact and expressive syntax for accessing, manipulating and operating on data in vectors, matrices and higher-dimensional arrays. NumPy is the primary array programming library for...
7.
Virtanen P, Gommers R, Oliphant T, Haberland M, Reddy T, Cournapeau D, et al.
Nat Methods
. 2020 Feb;
17(3):352.
PMID: 32094914
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
8.
Virtanen P, Gommers R, Oliphant T, Haberland M, Reddy T, Cournapeau D, et al.
Nat Methods
. 2020 Feb;
17(3):261-272.
PMID: 32015543
SciPy is an open-source scientific computing library for the Python programming language. Since its initial release in 2001, SciPy has become a de facto standard for leveraging scientific algorithms in...
9.
Chavent M, Duncan A, Rassam P, Birkholz O, Helie J, Reddy T, et al.
Nat Commun
. 2018 Jul;
9(1):2846.
PMID: 30030429
The spatiotemporal organisation of membranes is often characterised by the formation of large protein clusters. In Escherichia coli, outer membrane protein (OMP) clustering leads to OMP islands, the formation of...
10.
Duncan A, Reddy T, Koldso H, Helie J, Fowler P, Chavent M, et al.
Sci Rep
. 2017 Dec;
7(1):16647.
PMID: 29192147
Cell membranes are crowded and complex environments. To investigate the effect of protein-lipid interactions on dynamic organization in mammalian cell membranes, we have performed coarse-grained molecular dynamics simulations containing >100...