Matthias Wilm
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Explore the profile of Matthias Wilm including associated specialties, affiliations and a list of published articles.
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58
Citations
4191
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Recent Articles
1.
Nanoelectrospray based synthesis of large, transportable membranes with integrated membrane proteins
Wilm M
Sci Rep
. 2024 Oct;
14(1):25192.
PMID: 39448786
Membrane proteins tend to be difficult to study since they need to be integrated into a lipid bilayer membrane to function properly. This study presents a method to synthesize a...
2.
Bilgin M, Born P, Fezza F, Heimes M, Mastrangelo N, Wagner N, et al.
Sci Rep
. 2016 Jun;
6:27920.
PMID: 27312775
We present a method for the systematic identification of picogram quantities of new lipids in total extracts of tissues and fluids. It relies on the modularity of lipid structures and...
3.
Alfieri C, Gambetta M, Matos R, Glatt S, Sehr P, Fraterman S, et al.
Genes Dev
. 2013 Nov;
27(21):2367-79.
PMID: 24186981
Polycomb group (PcG) protein complexes repress developmental regulator genes by modifying their chromatin. How different PcG proteins assemble into complexes and are recruited to their target genes is poorly understood....
4.
Hahne H, Pachl F, Ruprecht B, Maier S, Klaeger S, Helm D, et al.
Nat Methods
. 2013 Aug;
10(10):989-91.
PMID: 23975139
We report that low percentages of dimethylsulfoxide (DMSO) in liquid chromatography solvents lead to a strong enhancement of electrospray ionization of peptides, improving the sensitivity of protein identification in bottom-up...
5.
Wilm M
Mol Cell Proteomics
. 2011 Jul;
10(7):M111.009407.
PMID: 21742801
Electrospray ionization is today the most widely used ionization technique in chemical and biochemical analysis. Interfaced with a mass spectrometer it allows the investigation of the molecular composition of liquid...
6.
Wilm M
Mol Cell Proteomics
. 2011 May;
PMID: 21597042
Electrospray ionization is today the most widely used ionization technique in chemical and bio-chemical analysis. Interfaced with a mass spectrometer it allows to investigate the molecular composition of liquid samples....
7.
Danckwardt S, Gantzert A, Macher-Goeppinger S, Probst H, Gentzel M, Wilm M, et al.
Mol Cell
. 2011 Feb;
41(3):298-310.
PMID: 21292162
Thrombin is a key protease involved in blood coagulation, complement activation, inflammation, angiogenesis, and tumor invasion. Although induced in many (patho-)physiological conditions, the underlying mechanisms controlling prothrombin expression remained enigmatic....
8.
Scheuermann J, de Ayala Alonso A, Oktaba K, Ly-Hartig N, McGinty R, Fraterman S, et al.
Nature
. 2010 May;
465(7295):243-7.
PMID: 20436459
Polycomb group (PcG) proteins are transcriptional repressors that control processes ranging from the maintenance of cell fate decisions and stem cell pluripotency in animals to the control of flowering time...
9.
Wilm M
Proteomics
. 2009 Sep;
9(20):4590-605.
PMID: 19743428
Proteomics has enabled the direct investigation of biological material, at first through the analysis of individual proteins, then of lysates from cell cultures, and finally of extracts from tissues and...
10.
Bonnal S, Martinez C, Forch P, Bachi A, Wilm M, Valcarcel J
Mol Cell
. 2008 Oct;
32(1):81-95.
PMID: 18851835
RBM5/Luca-15/H37 is a gene frequently inactivated in lung cancers and overexpressed in breast tumors. Its protein product has been detected in prespliceosomal complexes and modulates cell proliferation and Fas-mediated apoptosis....