Matthias Schlesner
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Explore the profile of Matthias Schlesner including associated specialties, affiliations and a list of published articles.
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149
Citations
17606
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Recent Articles
1.
Glaser S, Fischer A, Martinez-Manjon J, Lopez C, Kretzmer H, Burkhardt B, et al.
Leukemia
. 2025 Mar;
PMID: 40065077
No abstract available.
2.
Sahasrabuddhe A, Chen X, Ma K, Wu R, Liang H, Kapoor R, et al.
Cancer Discov
. 2025 Jan;
PMID: 39820335
The role of ubiquitin-mediated degradation mechanisms in the pathogenesis of diffuse large B cell (DLBCL) and follicular lymphoma (FL) is not completely understood. We show that conditional deletion of the...
3.
Gehrs S, Jakab M, Gutjahr E, Gu Z, Weichenhan D, Mallm J, et al.
Dev Cell
. 2025 Jan;
PMID: 39814015
The labyrinthian fetoplacental capillary network is vital for proper nourishment of the developing embryo. Dysfunction of the maternal-fetal circulation is a primary cause of placental insufficiency. Here, we show that...
4.
Glaser S, Kretzmer H, Kolassa I, Schlesner M, Fischer A, Fenske I, et al.
NAR Genom Bioinform
. 2024 Dec;
6(4):lqae181.
PMID: 39703427
Illumina-based BeadChip arrays have revolutionized genome-wide DNA methylation profiling, pushing it into diagnostics. However, comprehensive quality assessment remains challenging within a wide range of available tissue materials and sample preparation...
5.
Jayne S, Lopez C, Put N, Nagel I, Lierman E, Murga Penas E, et al.
Br J Haematol
. 2024 Oct;
205(6):2321-2326.
PMID: 39406248
The chromosomal translocation t(1;6)(p35.3;p25.2) is a rare but recurrent aberration in chronic lymphocytic leukaemia (CLL). We report molecular characterization of 10 cases and show that this translocation juxtaposes interferon regulatory...
6.
Fincke V, Steinbugl M, Chun H, Nemes K, Mucha M, Lossner M, et al.
Clin Cancer Res
. 2024 Aug;
30(20):4667-4680.
PMID: 39120581
Purpose: Extracranial malignant rhabdoid tumors (eMRT) are a challenging entity. Despite the use of multimodal treatment approaches, therapy failure occurs in 55% to 67% of these. Molecular markers for identification...
7.
Grimsrud M, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, et al.
Hepatol Commun
. 2024 Jul;
8(7).
PMID: 38967597
Background: People with primary sclerosing cholangitis (PSC) have a 20% lifetime risk of biliary tract cancer (BTC). Using whole-exome sequencing, we characterized genomic alterations in tissue samples from BTC with...
8.
Seiboldt T, Zeiser C, Nguyen D, Celikyurekli S, Herter S, Najafi S, et al.
Br J Cancer
. 2024 Jun;
131(4):763-777.
PMID: 38942989
Background: Certain paediatric nervous system malignancies have dismal prognoses. Retinoic acid (RA) is used in neuroblastoma treatment, and preclinical data indicate potential benefit in selected paediatric brain tumour entities. However,...
9.
Hai L, Hoffmann D, Wagener R, Azorin D, Hausmann D, Xie R, et al.
Nat Commun
. 2024 Feb;
15(1):968.
PMID: 38320988
Tumor microtubes (TMs) connect glioma cells to a network with considerable relevance for tumor progression and therapy resistance. However, the determination of TM-interconnectivity in individual tumors is challenging and the...
10.
Heuer S, Burghaus I, Gose M, Kessler T, Sahm F, Vollmuth P, et al.
BMC Cancer
. 2024 Jan;
24(1):135.
PMID: 38279087
Background: Glioblastoma is the most frequent and a particularly malignant primary brain tumor with no efficacy-proven standard therapy for recurrence. It has recently been discovered that excitatory synapses of the...