Matthias Preller
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Explore the profile of Matthias Preller including associated specialties, affiliations and a list of published articles.
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34
Citations
569
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Recent Articles
1.
Ewert W, Bartens C, Ongouta J, Holmes M, Heutling A, Kishore A, et al.
Nat Commun
. 2025 Mar;
16(1):2464.
PMID: 40075103
Amide synthases catalyze the formation of macrolactam rings from aniline-containing polyketide-derived seco-acids as found in the important class of ansamycin antibiotics. One of these amide synthases is the geldanamycin amide...
2.
Kyriazi D, Voth L, Bader A, Ewert W, Gerlach J, Elfrink K, et al.
Nat Commun
. 2024 Nov;
15(1):9947.
PMID: 39550360
Aberrant Ras homologous (Rho) GTPase signalling is a major driver of cancer metastasis, and GTPase-activating proteins (GAPs), the negative regulators of RhoGTPases, are considered promising targets for suppressing metastasis, yet...
3.
Lawong R, May F, Etang E, Vorrat P, George J, Weder J, et al.
Membranes (Basel)
. 2023 May;
13(5).
PMID: 37233590
The epithelial sodium channel (ENaC) is a key regulator of sodium homeostasis that contributes to blood pressure control. ENaC open probability is adjusted by extracellular sodium ions, a mechanism referred...
4.
Franz P, Ewert W, Preller M, Tsiavaliaris G
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36233360
The author wishes to make the following correction to this paper [...].
5.
Lin J, Gettings S, Talbi K, Schreiber R, Taggart M, Preller M, et al.
Pflugers Arch
. 2022 Oct;
475(2):167-179.
PMID: 36205782
The cystic fibrosis transmembrane conductance regulator (CFTR) anion channel and the epithelial Na channel (ENaC) play essential roles in transepithelial ion and fluid transport in numerous epithelial tissues. Inhibitors of...
6.
Fan L, Kishore A, Jansen-Olliges L, Wang D, Stahl F, Psathaki O, et al.
ACS Omega
. 2022 Aug;
7(33):28932-28945.
PMID: 36033668
While many proteins are known clients of heat shock protein 90 (Hsp90), it is unclear whether the transcription factor, thyroid hormone receptor beta (TRb), interacts with Hsp90 to control hormonal...
7.
Fan L, Warnecke A, Weder J, Preller M, Zeilinger C
Int J Mol Sci
. 2022 Jul;
23(13).
PMID: 35806154
Microarray-based experiments revealed that thyroid hormone triiodothyronine (T3) enhanced the binding of Cy5-labeled ATP on heat shock protein 90 (Hsp90). By molecular docking experiments with T3 on Hsp90, we identified...
8.
Forster A, Brand F, Banan R, Huneburg R, Weber C, Ewert W, et al.
Acta Neuropathol
. 2021 Apr;
142(1):191-210.
PMID: 33929593
The genetic basis of brain tumor development is poorly understood. Here, leukocyte DNA of 21 patients from 15 families with ≥ 2 glioma cases each was analyzed by whole-genome or...
9.
Franz P, Ewert W, Preller M, Tsiavaliaris G
Int J Mol Sci
. 2020 Dec;
22(1).
PMID: 33374308
The actomyosin system generates mechanical work with the execution of the power stroke, an ATP-driven, two-step rotational swing of the myosin-neck that occurs post ATP hydrolysis during the transition from...
10.
Ewert W, Franz P, Tsiavaliaris G, Preller M
Int J Mol Sci
. 2020 Oct;
21(19).
PMID: 33049993
The motor protein myosin drives a wide range of cellular and muscular functions by generating directed movement and force, fueled through adenosine triphosphate (ATP) hydrolysis. Release of the hydrolysis product...