Matthias Muhar
Overview
Explore the profile of Matthias Muhar including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
2004
Followers
0
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Recent Articles
11.
Rathert P, Roth M, Neumann T, Muerdter F, Roe J, Muhar M, et al.
Nature
. 2015 Sep;
525(7570):543-547.
PMID: 26367798
Following the discovery of BRD4 as a non-oncogene addiction target in acute myeloid leukaemia (AML), bromodomain and extra terminal protein (BET) inhibitors are being explored as a promising therapeutic avenue...
12.
Fellmann C, Hoffmann T, Sridhar V, Hopfgartner B, Muhar M, Roth M, et al.
Cell Rep
. 2013 Dec;
5(6):1704-13.
PMID: 24332856
Short hairpin RNA (shRNA) technology enables stable and regulated gene repression. For establishing experimentally versatile RNAi tools and minimizing toxicities, synthetic shRNAs can be embedded into endogenous microRNA contexts. However,...
13.
Shi J, Whyte W, Zepeda-Mendoza C, Milazzo J, Shen C, Roe J, et al.
Genes Dev
. 2013 Nov;
27(24):2648-62.
PMID: 24285714
Cancer cells frequently depend on chromatin regulatory activities to maintain a malignant phenotype. Here, we show that leukemia cells require the mammalian SWI/SNF chromatin remodeling complex for their survival and...
14.
Wienerroither S, Rauch I, Rosebrock F, Jamieson A, Bradner J, Muhar M, et al.
Mol Cell Biol
. 2013 Nov;
34(3):415-27.
PMID: 24248598
Transcriptional activation of the Nos2 gene, encoding inducible nitric oxide synthase (iNOS), during infection or inflammation requires coordinate assembly of an initiation complex by the transcription factors NF-κB and type...
15.
Kamnev A, Muhar M, Preinreich M, Ammer H, Propst F
PLoS One
. 2013 Jul;
8(6):e68168.
PMID: 23840827
Protein S-nitrosylation, the covalent attachment of a nitroso moiety to thiol groups of specific cysteine residues, is one of the major pathways of nitric oxide signaling. Hundreds of proteins are...