Matthias Hackl
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Explore the profile of Matthias Hackl including associated specialties, affiliations and a list of published articles.
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122
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2173
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Recent Articles
1.
Haschka J, Messner Z, Feurstein J, Hadzimuratovic B, Zwerina J, Diendorfer A, et al.
J Clin Endocrinol Metab
. 2025 Feb;
PMID: 39930630
Introduction: Adult hypophosphatasia (HPP) patients present with diffuse heterogenous symptoms often mimicking rheumatological diseases or osteoporosis and therefore accompanied by delayed diagnosis. The aim of this study was to identify...
2.
Daamouch S, Diendorfer A, Hackl M, Christoffel G, Hofbauer L, Rauner M
Front Endocrinol (Lausanne)
. 2025 Jan;
15():1477257.
PMID: 39777220
Type 1 diabetes (T1D) represents a significant health burden worldwide, with associated complications including bone fragility. Current clinical methods and biomarkers for assessing bone health and predicting fracture risk in...
3.
Carro Vazquez D, Emini L, Rauner M, Hofbauer C, Skalicky S, Wagner A, et al.
JBMR Plus
. 2024 Dec;
9(1):ziae121.
PMID: 39664932
Type 2 diabetes mellitus (T2DM) increases the susceptibility of bone fragility. The underlying mechanisms have, however, remained largely unknown. MicroRNAs (miRNAs) are short single-stranded non-coding RNA molecules with utility as...
4.
Bobbili M, Gorgens A, Yan Y, Vogt S, Gupta D, Corso G, et al.
J Extracell Vesicles
. 2024 Oct;
13(10):e12523.
PMID: 39400515
Extracellular vesicles (EVs) are lipid nanoparticles and play an important role in cell-cell communications, making them potential therapeutic agents and allowing to engineer for targeted drug delivery. The expanding applications...
5.
Hadzimuratovic B, Haschka J, Hackl M, Diendorfer A, Mittelbach A, Feurstein J, et al.
JBMR Plus
. 2024 Sep;
8(10):ziae107.
PMID: 39224569
Hypophosphatasia (HPP) is characterized by low activity of tissue nonspecific alkaline phosphatase (TNSALP). The enzyme replacement therapy asfotase alfa has been approved for childhood-onset forms of HPP. MicroRNAs (miRNAs) have...
6.
Schaubmayr W, Hackl M, Pultar M, Ghanim B, Klein K, Schmid J, et al.
Int J Mol Sci
. 2024 Aug;
25(16).
PMID: 39201485
Oxygen conditions in the lung determine downstream organ functionality by setting the partial pressure of oxygen, regulating the redox homeostasis and by activating mediators in the lung that can be...
7.
Pultar M, Oesterreicher J, Hartmann J, Weigl M, Diendorfer A, Schimek K, et al.
J Extracell Biol
. 2024 Jun;
3(1):e134.
PMID: 38938681
Extracellular vesicles (EVs) are crucial mediators of cell-to-cell communication in physiological and pathological conditions. Specifically, EVs released from the vasculature into blood were found to be quantitatively and qualitatively different...
8.
Wachtel H, Ermer J, Fraker D, Kelz R, Kelly T, Hackl M, et al.
Ann Surg
. 2024 Jun;
280(4):584-594.
PMID: 38881439
Objective: The goal of this study was to characterize the microRNA (miRNA) expression signatures in patients with Primary hyperparathyroidism (PHPT) and identify miRNA biomarkers of bone homeostasis. Background: PHPT is...
9.
Paksoy A, Meller S, Schwotzer F, Moroder P, Trampuz A, Imiolczyk J, et al.
Bone Jt Open
. 2024 Jun;
5(6):479-488.
PMID: 38839054
Aims: Current diagnostic tools are not always able to effectively identify periprosthetic joint infections (PJIs). Recent studies suggest that circulating microRNAs (miRNAs) undergo changes under pathological conditions such as infection....
10.
Weigl M, Krammer T, Pultar M, Wieser M, Chaib S, Suda M, et al.
bioRxiv
. 2024 Apr;
PMID: 38645053
In the last decade cellular senescence, a hallmark of aging, has come into focus for pharmacologically targeting aging processes. Senolytics are one of these interventive strategies that have advanced into...