Marcel Scheideler
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Explore the profile of Marcel Scheideler including associated specialties, affiliations and a list of published articles.
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64
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2166
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Recent Articles
1.
Giroud M, Kotschi S, Kwon Y, Le Thuc O, Hoffmann A, Gil-Lozano M, et al.
EMBO Rep
. 2023 Sep;
24(10):e57600.
PMID: 37671834
Adipocytes are critical regulators of metabolism and energy balance. While white adipocyte dysfunction is a hallmark of obesity-associated disorders, thermogenic adipocytes are linked to cardiometabolic health. As adipocytes dynamically adapt...
2.
Kornmueller K, Amri E, Scheideler M, Prassl R
Adv Drug Deliv Rev
. 2022 Jan;
181:114110.
PMID: 34995679
Despite the increasing prevalence of obesity and diabetes, there is no efficient treatment to combat these epidemics. The adipose organ is the main site for energy storage and plays a...
3.
Georgiadi A, Lopez-Salazar V, Merahbi R, Karikari R, Ma X, Mourao A, et al.
Nat Commun
. 2021 May;
12(1):2999.
PMID: 34016966
The proper functional interaction between different tissues represents a key component in systemic metabolic control. Indeed, disruption of endocrine inter-tissue communication is a hallmark of severe metabolic dysfunction in obesity...
4.
Giroud M, Tsokanos F, Caratti G, Kotschi S, Khani S, Jouffe C, et al.
Diabetologia
. 2021 May;
64(8):1850-1865.
PMID: 34014371
Aims/hypothesis: Adipocytes are critical cornerstones of energy metabolism. While obesity-induced adipocyte dysfunction is associated with insulin resistance and systemic metabolic disturbances, adipogenesis, the formation of new adipocytes and healthy adipose...
5.
Pleitez M, Ali Khan A, Solda A, Chmyrov A, Reber J, Gasparin F, et al.
Nat Biotechnol
. 2019 Dec;
38(3):293-296.
PMID: 31873214
We develop mid-infrared optoacoustic microscopy (MiROM) for label-free, bond-selective, live-cell metabolic imaging, enabling spatiotemporal monitoring of carbohydrates, lipids and proteins in cells and tissues. Using acoustic detection of optical absorption,...
6.
Scheideler M, Vidakovic I, Prassl R
Chem Phys Lipids
. 2019 Nov;
226:104837.
PMID: 31689410
Non-coding RNAs (ncRNAs) like microRNAs (miRNAs) or small interference RNAs (siRNAs) with their power to selectively silence any gene of interest enable the targeting of so far 'undruggable' proteins and...
7.
Glantschnig C, Mattijssen F, Vogl E, Ali Khan A, Garcia M, Fischer K, et al.
EMBO Rep
. 2019 Sep;
20(11):e48552.
PMID: 31559673
Aberrant activity of the glucocorticoid (GC)/glucocorticoid receptor (GR) endocrine system has been linked to obesity-related metabolic dysfunction. Traditionally, the GC/GR axis has been believed to play a crucial role in...
8.
Glantschnig C, Koenen M, Gil-Lozano M, Karbiener M, Pickrahn I, Williams-Dautovich J, et al.
FASEB J
. 2019 Feb;
33(5):5924-5941.
PMID: 30742779
The glucocorticoid receptor (GR) represents the crucial molecular mediator of key endocrine, glucocorticoid hormone-dependent regulatory circuits, including control of glucose, protein, and lipid homeostasis. Consequently, aberrant glucocorticoid signaling is linked...
9.
Scheideler M
Handb Exp Pharmacol
. 2018 Nov;
251:215-237.
PMID: 30478736
Brite/brown adipose tissue (BAT) is a thermogenic tissue able to dissipate energy via non-shivering thermogenesis. It is naturally activated by cold and has been demonstrated to increase thermogenic capacity, elevate...
10.
Higareda-Almaraz J, Karbiener M, Giroud M, Pauler F, Gerhalter T, Herzig S, et al.
BMC Genomics
. 2018 Nov;
19(1):794.
PMID: 30390616
Background: Norepinephrine (NE) signaling has a key role in white adipose tissue (WAT) functions, including lipolysis, free fatty acid liberation and, under certain conditions, conversion of white into brite (brown-in-white)...