Cristina Garcia-Caceres
Overview
Explore the profile of Cristina Garcia-Caceres including associated specialties, affiliations and a list of published articles.
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Articles
72
Citations
2430
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Recent Articles
1.
Freire-Agulleiro O, Estevez-Salguero A, Ferreira V, Holleman C, Garcia-Curras J, Gonzalez-Garcia I, et al.
Mol Metab
. 2025 Jan;
92:102091.
PMID: 39746605
Objective: AMP-activated protein kinase (AMPK) is a heterotrimer complex consisting of a catalytic α subunit (α1, α2) with a serine/threonine kinase domain, and two regulatory subunits, β (β1, β2) and...
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Contreras R, Gruber T, Gonzalez-Garcia I, Schriever S, De Angelis M, Mallet N, et al.
Mol Metab
. 2024 Sep;
90:102033.
PMID: 39304061
With age, metabolic perturbations accumulate to elevate our obesity burden. While age-onset obesity is mostly driven by a sedentary lifestyle and high calorie intake, genetic and epigenetic factors also play...
4.
Goll N, Moszka N, Kantartzis K, Preissl H, Gruber T, Fritsche L, et al.
Diabetes Obes Metab
. 2024 Aug;
26(10):4562-4570.
PMID: 39118203
Aim: To assess oxytocin's acute glucoregulatory impact in men with type 2 diabetes in the context of our previous findings that oxytocin improves β-cell responsivity in healthy men. Methods: In...
5.
Le Thuc O, Garcia-Caceres C
Nat Metab
. 2024 Jul;
6(7):1237-1252.
PMID: 38997442
Obesity is often associated with a chronic, low-grade inflammatory state affecting the entire body. This sustained inflammatory state disrupts the coordinated communication between the periphery and the brain, which has...
6.
Gruber T, Lechner F, Krieger J, Garcia-Caceres C
Trends Endocrinol Metab
. 2024 May;
36(1):42-54.
PMID: 38821753
The past decades have witnessed the rise and fall of several, largely unsuccessful, therapeutic attempts to bring the escalating obesity pandemic to a halt. Looking back to look ahead, the...
7.
Akindehin S, Liskiewicz A, Liskiewicz D, Bernecker M, Garcia-Caceres C, Drucker D, et al.
Mol Metab
. 2024 Mar;
83:101915.
PMID: 38492844
Objective: The glucose-dependent insulinotropic polypeptide (GIP) decreases body weight via central GIP receptor (GIPR) signaling, but the underlying mechanisms remain largely unknown. Here, we assessed whether GIP regulates body weight...
8.
Grandl G, Collden G, Feng J, Bhattacharya S, Klingelhuber F, Schomann L, et al.
Nat Metab
. 2024 Feb;
6(3):448-457.
PMID: 38418586
Insulin resistance is an early complication of diet-induced obesity (DIO), potentially leading to hyperglycaemia and hyperinsulinaemia, accompanied by adaptive β cell hypertrophy and development of type 2 diabetes. Insulin not...
9.
Gonzalez-Vila A, Luengo-Mateos M, Silveira-Loureiro M, Garrido-Gil P, Ohinska N, Gonzalez-Dominguez M, et al.
Nat Commun
. 2023 Dec;
14(1):8175.
PMID: 38071352
Mammalian circadian clocks respond to feeding and light cues, adjusting internal rhythms with day/night cycles. Astrocytes serve as circadian timekeepers, driving daily physiological rhythms; however, it's unknown how they ensure...
10.
Gruber T, Lechner F, Murat C, Contreras R, Sanchez-Quant E, Miok V, et al.
Cell Rep
. 2023 Oct;
42(10):113305.
PMID: 37864798
Oxytocin-expressing paraventricular hypothalamic neurons (PVN neurons) integrate afferent signals from the gut, including cholecystokinin (CCK), to adjust whole-body energy homeostasis. However, the molecular underpinnings by which PVN neurons orchestrate gut-to-brain...