Matthew T Birnie
Overview
Explore the profile of Matthew T Birnie including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
346
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Taniguchi L, Goodpaster C, De Carvalho G, Birnie M, Chen Y, Chen L, et al.
bioRxiv
. 2024 Dec;
PMID: 39651305
Background: Motivated behaviors are executed by refined brain circuits. Early-life adversity (ELA) is a risk for human affective disorders involving dysregulated reward behaviors. In mice, ELA causes anhedonia-like behaviors in...
2.
Baram T, Birnie M
Neurobiol Stress
. 2024 Sep;
33:100669.
PMID: 39309367
Adverse early life experiences are strongly associated with reduced cognitive function throughout life. The link is strong in many human studies, but these do not enable assigning causality, and the...
3.
Kooiker C, Birnie M, Floriou-Servou A, Ding Q, Thiagarajan N, Hardy M, et al.
bioRxiv
. 2024 May;
PMID: 38746198
Early-life adversity increases risk for mental illnesses including depression and substance use disorders, disorders characterized by dysregulated reward behaviors. However, the mechanisms by which transient ELA enduringly impacts reward circuitries...
4.
Kooiker C, Chen Y, Birnie M, Baram T
Biol Psychiatry Glob Open Sci
. 2023 Oct;
3(4):746-755.
PMID: 37881549
Background: Early-life adversity (ELA) is associated with increased risk for mood disorders, including depression and substance use disorders. These disorders are characterized by impaired reward-related behaviors, suggesting compromised operations of...
5.
Birnie M, Claydon M, Troy O, Flynn B, Yoshimura M, Kershaw Y, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(15):e2211996120.
PMID: 37023133
Disrupted circadian activity is associated with many neuropsychiatric disorders. A major coordinator of circadian biological systems is adrenal glucocorticoid secretion which exhibits a pronounced preawakening peak that regulates metabolic, immune,...
6.
Birnie M, Short A, de Carvalho G, Taniguchi L, Gunn B, Pham A, et al.
Nat Commun
. 2023 Feb;
14(1):1088.
PMID: 36841826
Disrupted operations of the reward circuit underlie major emotional disorders, including depression, which commonly arise following early life stress / adversity (ELA). However, how ELA enduringly impacts reward circuit functions...
7.
Short A, Thai C, Chen Y, Kamei N, Pham A, Birnie M, et al.
Biol Psychiatry Glob Open Sci
. 2023 Jan;
3(1):99-109.
PMID: 36712559
Background: Mental health and vulnerabilities to neuropsychiatric disorders involve the interplay of genes and environment, particularly during sensitive developmental periods. Early-life adversity (ELA) and stress promote vulnerabilities to stress-related affective...
8.
Stubbs F, Flynn B, Rivers C, Birnie M, Herman A, Swinstead E, et al.
Oncogene
. 2022 Nov;
41(50):5347-5360.
PMID: 36344675
ARID1a (BAF250), a component of human SWI/SNF chromatin remodeling complexes, is frequently mutated across numerous cancers, and its loss of function has been putatively linked to glucocorticoid resistance. Here, we...
9.
Birnie M, Eapen A, Kershaw Y, Lodge D, Collingridge G, Conway-Campbell B, et al.
J Neuroendocrinol
. 2022 Sep;
34(10):e13194.
PMID: 36056546
Over 50% of depressed patients show hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Conventional therapy takes weeks to months to improve symptoms. Ketamine has rapid onset antidepressant effects. Yet its action...
10.
Levis S, Birnie M, Bolton J, Perrone C, Montesinos J, Baram T, et al.
Transl Psychiatry
. 2022 Jun;
12(1):251.
PMID: 35705547
In humans, early-life adversity (ELA) such as trauma, poverty, and chaotic environment is linked to increased risk of later-life emotional disorders including depression and substance abuse. These disorders involve underlying...