Stephen V Mahler
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Explore the profile of Stephen V Mahler including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Hubbard E, Derdeyn P, Galinato V, Wu A, Bartas K, Mahler S, et al.
Neuropsychopharmacology
. 2024 Dec;
PMID: 39658631
Use of one addictive drug typically influences the behavioral response to other drugs, either administered at the same time or a subsequent time point. The nature of the drugs being...
2.
Martinez M, Vera V, Ruiz C, Floresco S, Mahler S
Psychopharmacology (Berl)
. 2024 Aug;
242(2):309-326.
PMID: 39190156
Rationale: Adolescent cannabis use is linked to later-life changes in cognition, learning, and memory. Rodent experimental studies suggest Δ-tetrahydrocannabinol (THC) influences development of circuits underlying these processes, especially in the...
3.
Martinez M, Vera V, Ruiz C, Floresco S, Mahler S
bioRxiv
. 2024 Jun;
PMID: 38826339
Rationale: Adolescent cannabis use is linked to later-life changes in cognition, learning, and memory. Rodent experimental studies suggest Δ-tetrahydrocannabinol (THC) influences development of circuits underlying these processes, especially in the...
4.
Lawson K, Ruiz C, Mahler S
Psychopharmacology (Berl)
. 2023 Aug;
240(10):2101-2110.
PMID: 37530882
Rationale: Designer receptors exclusively activated by designer drugs (DREADDs) are a tool for "remote control" of defined neuronal populations during behavior. These receptors are inert unless bound by an experimenter-administered...
5.
Lawson K, Ruiz C, Mahler S
bioRxiv
. 2023 Apr;
PMID: 37034819
Rationale: Designer receptors exclusively activated by designer drugs (DREADDs) are a tool for "remote control" of defined neuronal populations during behavior. These receptors are inert unless bound by an experimenter-administered...
6.
Halbout B, Hutson C, Hua L, Inshishian V, Mahler S, Ostlund S
Psychopharmacology (Berl)
. 2023 Mar;
240(5):1151-1167.
PMID: 36933028
Rationale: The endocannabinoid system makes critical contributions to reward processing, motivation, and behavioral control. Repeated exposure to THC or other cannabinoid drugs can cause persistent adaptions in the endocannabinoid system...
7.
Lim J, Lee H, Nguyen J, Shin J, Getze S, Quach C, et al.
Toxicol Sci
. 2023 Mar;
193(1):31-47.
PMID: 36912754
Cannabis use by adolescents is widespread, but its effects on the ovaries remain largely unknown. Δ9-tetrahydrocannabinol (THC) exerts its pharmacological effects by activating, and in some conditions hijacking, cannabinoid receptors...
8.
Birnie M, Short A, de Carvalho G, Taniguchi L, Gunn B, Pham A, et al.
Nat Commun
. 2023 Feb;
14(1):1088.
PMID: 36841826
Disrupted operations of the reward circuit underlie major emotional disorders, including depression, which commonly arise following early life stress / adversity (ELA). However, how ELA enduringly impacts reward circuit functions...
9.
Torrens A, Ruiz C, Martinez M, Mabou Tagne A, Roy P, Grimes D, et al.
Pharmacol Res
. 2022 Dec;
187:106600.
PMID: 36481259
Passive aerosol exposure to Δ-tetrahydrocannabinol (THC) in laboratory animals results in faster onset of action and less extensive liver metabolism compared to most other administration routes and might thus provide...
10.
Ahmed F, Torrens A, Mahler S, Ferlenghi F, Huestis M, Piomelli D
Cannabis Cannabinoid Res
. 2022 Nov;
9(1):371-385.
PMID: 36367975
Δ-tetrahydrocannabinol (THC) and cannabidiol (CBD) are major chemical constituents of cannabis, which may interact either directly or indirectly with the endocannabinoid and endocannabinoid-like ("paracannabinoid") systems, two lipid-based signaling complexes that...