Matthew T Birnie
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Explore the profile of Matthew T Birnie including associated specialties, affiliations and a list of published articles.
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Citations
346
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Recent Articles
11.
Birnie M, Baram T
Science
. 2022 Jun;
376(6597):1055-1056.
PMID: 35653483
Early-life environmental signals contribute to how the brain handles reward, stress, and fear.
12.
Birnie M, Levis S, Mahler S, Baram T
Curr Top Behav Neurosci
. 2022 Feb;
58:23-41.
PMID: 35156184
This chapter discusses how the complex concept of anhedonia can be operationalized and studied in preclinical models. It provides information about the development of anhedonia in the context of early-life...
13.
Kark S, Birnie M, Baram T, Yassa M
Front Integr Neurosci
. 2021 Aug;
15:724071.
PMID: 34381338
[This corrects the article DOI: 10.3389/fnint.2021.662293.].
14.
Flynn B, Birnie M, Kershaw Y, Pauza A, Kim S, Baek S, et al.
PLoS Genet
. 2021 Aug;
17(8):e1009737.
PMID: 34375333
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a...
15.
Kooiker C, Birnie M, Baram T
Front Behav Neurosci
. 2021 Jun;
15:673162.
PMID: 34079442
Early-life experiences influence a broad spectrum of behaviors throughout the lifespan that contribute to resilience or vulnerability to mental health disorders. Yet, how emotionally salient experiences early in life are...
16.
Kark S, Birnie M, Baram T, Yassa M
Front Integr Neurosci
. 2021 May;
15:662293.
PMID: 33967711
The paraventricular thalamic nucleus (PVT) is a small but highly connected nucleus of the dorsal midline thalamus. The PVT has garnered recent attention as a context-sensitive node within the thalamocortical...
17.
Birnie M, Kooiker C, Short A, Bolton J, Chen Y, Baram T
Biol Psychiatry
. 2020 Feb;
87(10):875-884.
PMID: 32081365
Disrupted operation of the reward circuitry underlies many aspects of affective disorders. Such disruption may manifest as aberrant behavior including risk taking, depression, anhedonia, and addiction. Early-life adversity is a...
18.
Lightman S, Birnie M, Conway-Campbell B
Endocr Rev
. 2020 Feb;
41(3).
PMID: 32060528
The past decade has seen several critical advances in our understanding of hypothalamic-pituitary-adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate multiple internal and external stimuli and provide a...
19.
Pooley J, Flynn B, Grontved L, Baek S, Guertin M, Kershaw Y, et al.
Endocrinology
. 2017 Feb;
158(5):1486-1501.
PMID: 28200020
Glucocorticoids regulate hippocampal function in part by modulating gene expression through the glucocorticoid receptor (GR). GR binding is highly cell type specific, directed to accessible chromatin regions established during tissue...
20.
George C, Birnie M, Flynn B, Kershaw Y, Lightman S, Conway-Campbell B
Mol Cell Endocrinol
. 2016 Nov;
439:46-53.
PMID: 27769714
In this paper we report differential decoding of the ultradian corticosterone signal by glucocorticoid target tissues. Pulsatile corticosterone replacement in adrenalectomised rats resulted in different dynamics of Sgk1 mRNA production,...