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Matthew R Kudelka

Explore the profile of Matthew R Kudelka including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 671
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Recent Articles
1.
Kudelka M, Richards A, Friedlander P, Wolchok J, Moy A, Shoushtari A
J Immunother Cancer . 2024 Nov; 12(11). PMID: 39551602
Melanoma arising in association with a blue nevus (BN) is rare but has molecular similarities to uveal melanoma (UM), including GNAQ/11 mutations. Tebentafusp was recently approved for UM based on...
2.
Kudelka M, Lavin Y, Sun S, Fuchs E
Genes Dev . 2024 Oct; 39(1-2):18-35. PMID: 39455281
Squamous cell carcinomas (SCCs), arising from the skin, head and neck, lungs, esophagus, and cervix, are collectively among the most common cancers and a frequent cause of cancer morbidity and...
3.
Kudelka M, Abou-Alfa G, OReilly E, Foote M, Sirohi B, Elias R, et al.
J Gastrointest Oncol . 2023 Sep; 14(4):1878-1886. PMID: 37720425
Background: Less than two percent of pancreatic neuroendocrine tumors (NETs) produce serotonin. Serotonin can cause carcinoid syndrome and less commonly carcinoid heart disease (CHD). CHD is associated with increased mortality...
4.
Kudelka M, Gu W, Matsumoto Y, Ju T, Barnes Ii R, Kardish R, et al.
Glycobiology . 2023 May; 33(7):567-578. PMID: 37216646
There is an urgent need to develop new tumor biomarkers for early cancer detection, but the variability of tumor-derived antigens has been a limitation. Here we demonstrate a novel anti-Tn...
5.
Kudelka M, Lasanajak Y, Smith D, Song X, Hossain M, Owonikoko T
Cancer Med . 2022 Nov; 12(6):6768-6777. PMID: 36437732
Purpose: Thyroid cancer recurrence following curative thyroidectomy is associated with increased morbidity and mortality, but current surveillance strategies are inadequate for early detection. Prior studies indicate that tissue glycosylation is...
6.
Kudelka M, Li Z, Chernova T, Smith D, Song X, Cummings R, et al.
Curr Protoc . 2021 Jun; 1(6):e142. PMID: 34101390
Mucin-type O-glycosylation (O-glycans, O-glycome) is among the most biologically important post-translational modification in glycoproteins but O-glycan structural diversity and expression are poorly understood due to the inadequacy of current analytical...
7.
Park D, Chen J, Kudelka M, Jia N, Haller C, Kosaraju R, et al.
Cell Chem Biol . 2020 Dec; 28(4):567-582.e4. PMID: 33378651
The pleiotropic functions of macrophages in immune defense, tissue repair, and maintenance of tissue homeostasis are supported by the heterogeneity in macrophage sub-populations that differ both in ontogeny and polarization....
8.
Zeng J, Eljalby M, Aryal R, Lehoux S, Stavenhagen K, Kudelka M, et al.
Nat Commun . 2020 Aug; 11(1):3990. PMID: 32778659
The molecular mechanisms regulating lymphocyte homing into lymph nodes are only partly understood. Here, we report that B cell-specific deletion of the X-linked gene, Cosmc, and the consequent decrease of...
9.
Kudelka M, Stowell S, Cummings R, Neish A
Nat Rev Gastroenterol Hepatol . 2020 Jul; 17(10):597-617. PMID: 32710014
Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors have been implicated in IBD pathogenesis, including host genetics, immune dysregulation and gut microbiota alterations. Emerging evidence...
10.
Kudelka M, Switchenko J, Lechowicz M, Esiashvili N, Flowers C, Khan M, et al.
Clin Lymphoma Myeloma Leuk . 2020 Jul; 20(11):757-767.e3. PMID: 32703750
Background: Treatment of cutaneous T-cell lymphoma (CTCL) with total skin electron beam (TSEB) therapy has been associated with deep responses but short progression-free intervals. Maintenance therapy might prolong the response...