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Matthew H Todd

Explore the profile of Matthew H Todd including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 1051
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Recent Articles
31.
Wong J, Todd M, Rutledge P
Molecules . 2017 Jan; 22(2). PMID: 28125069
Small-molecule fluorescent probes play a myriad of important roles in chemical sensing. Many such systems incorporating a receptor component designed to recognise and bind a specific analyte, and a reporter...
32.
Williamson A, Ylioja P, Robertson M, Antonova-Koch Y, Avery V, Baell J, et al.
ACS Cent Sci . 2016 Nov; 2(10):687-701. PMID: 27800551
The development of new antimalarial compounds remains a pivotal part of the strategy for malaria elimination. Recent large-scale phenotypic screens have provided a wealth of potential starting points for hit-to-lead...
33.
Wong J, Ast S, Yu M, Flehr R, Counsell A, Turner P, et al.
ChemistryOpen . 2016 Aug; 5(4):375-85. PMID: 27547648
Fluorescent molecular probes for metal ions have a raft of potential applications in chemistry and biomedicine. We report the synthesis and photophysical characterisation of 1,8-disubstituted-cyclam/naphthalimide conjugates and their zinc complexes....
34.
Yu M, Nagalingam G, Ellis S, Martinez E, Sintchenko V, Spain M, et al.
J Med Chem . 2016 May; 59(12):5917-21. PMID: 27214150
Tuberculosis (TB) accounted for 1.5 million deaths in 2014, and new classes of anti-TB drugs are required. We report a class of functionalized 1,8-disubstituted cyclam derivatives that display low micromolar...
35.
Todd M, Coaker H
Future Med Chem . 2015 May; 7(6):689-92. PMID: 25996061
No abstract available.
36.
Yu M, Wong J, Tang C, Turner P, Todd M, Rutledge P
Beilstein J Org Chem . 2015 Feb; 11:37-41. PMID: 25670990
The effective and efficient removal of the BF2 moiety from F-BODIPY derivatives has been achieved using two common Brønsted acids; treatment with trifluoroacetic acid (TFA) or methanolic hydrogen chloride (HCl)...
37.
Badiola K, Quan D, Triccas J, Todd M
PLoS One . 2014 Dec; 9(12):e111782. PMID: 25493550
Tuberculosis afflicts an estimated 2 billion people worldwide and causes 1.3 million deaths annually. Chemotherapeutic solutions rely on drugs developed many years ago, with only one new therapeutic having been...
38.
Ast S, Rutledge P, Todd M
Faraday Discuss . 2014 Dec; 175:171-87. PMID: 25483149
We report fluorescence measurements of three quantum dots (QDs) of different sizes functionalised with the same pH responsive naphthalimide dye. QD size strongly influences energy transfer between dye and dot....
39.
Yu M, Ryan T, Ellis S, Bush A, Triccas J, Rutledge P, et al.
Metallomics . 2014 Aug; 6(10):1931-40. PMID: 25132118
Interactions between amyloid β (Aβ) and metal ions are thought to mediate the neuropathogenic effects of Aβ in Alzheimer's disease. The construction of small molecules capable of synergistically chelating metal...
40.
Yu M, Ast S, Yu Q, Lo A, Flehr R, Todd M, et al.
PLoS One . 2014 Jul; 9(7):e100761. PMID: 24983863
Ligands incorporating a tetraazamacrocycle receptor, a 'click'-derived triazole and a 1,8-naphthalimide fluorophore have proven utility as probes for metal ions. Three new cyclam-based molecular probes are reported, in which a...