Matthew A Quinn
Overview
Explore the profile of Matthew A Quinn including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
18
Citations
322
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mainali R, Buechler N, Otero C, Edwards L, Key C, Furdui C, et al.
Elife
. 2024 Feb;
12.
PMID: 38305778
One primary metabolic manifestation of inflammation is the diversion of cis-aconitate within the tricarboxylic acid (TCA) cycle to synthesize the immunometabolite itaconate. Itaconate is well established to possess immunomodulatory and...
2.
Meyers A, Wang Z, Han W, Zhao Q, Zabalawi M, Duan L, et al.
Cell Rep
. 2023 Jan;
42(1):111941.
PMID: 36640341
Activating the macrophage NLRP3 inflammasome can promote excessive inflammation with severe cell and tissue damage and organ dysfunction. Here, we show that pharmacological or genetic inhibition of pyruvate dehydrogenase kinase...
3.
McCall C, Zhu X, Zabalawi M, Long D, Quinn M, Yoza B, et al.
J Leukoc Biol
. 2022 Jul;
112(6):1509-1514.
PMID: 35866365
Balancing high energy-consuming danger resistance and low energy supply of disease tolerance is a universal survival principle that often fails during sepsis. Our research supports the concept that sepsis phosphorylates...
4.
Oh T, Zabalawi M, Jain S, Long D, Stacpoole P, McCall C, et al.
JCI Insight
. 2022 Jun;
7(12).
PMID: 35730570
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection. The metabolic aberrations associated with sepsis underly an acute and organism-wide hyperinflammatory response and multiple organ...
5.
Oh T, Hutchins D, Mainali R, Goslen K, Quinn M
Front Immunol
. 2022 Mar;
13:748375.
PMID: 35265064
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects. While itaconate and its derivatives pose an attractive...
6.
Mainali R, Zabalawi M, Long D, Buechler N, Quillen E, Key C, et al.
Elife
. 2021 Feb;
10.
PMID: 33616039
Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their...
7.
Gera S, Sant D, Haider S, Korkmaz F, Kuo T, Mathew M, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(46):28971-28979.
PMID: 33127753
Blocking the action of FSH genetically or pharmacologically in mice reduces body fat, lowers serum cholesterol, and increases bone mass, making an anti-FSH agent a potential therapeutic for three global...
8.
Plant M, Armstrong C, Ruggiero A, Sherrill C, Uberseder B, Jeffries R, et al.
Geroscience
. 2020 Jun;
42(6):1649-1661.
PMID: 32588342
The trend to delay pregnancy in the USA has resulted in the number of advanced maternal age (AMA) pregnancies to also increase. In humans, AMA is associated with a variety...
9.
Gibson E, Bennett F, Gillespie S, Guler A, Gutmann D, Halpern C, et al.
Cell
. 2020 Jun;
181(7):1445-1449.
PMID: 32533917
The COVID19 crisis has magnified the issues plaguing academic science, but it has also provided the scientific establishment with an unprecedented opportunity to reset. Shoring up the foundation of academic...
10.
Key C, Bishop A, Wang X, Zhao Q, Chen G, Quinn M, et al.
J Lipid Res
. 2020 May;
61(7):1075-1086.
PMID: 32430316
The glycerol phosphate pathway produces more than 90% of the liver triacylglycerol (TAG). LysoPA, an intermediate in this pathway, is produced by glycerol-3-phosphate acyltransferase. Glycerophosphodiester phosphodiesterase domain containing 3 (GDPD3),...