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Charles E McCall

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Articles 106
Citations 3602
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Recent Articles
1.
Bah I, Youssef D, Yao Z, McCall C, El Gazzar M
J Clin Cell Immunol . 2024 Dec; 14(4). PMID: 39665047
During the acute phase of sepsis, the S100A9 proinflammatory protein resides in the cytosol in a phosphorylated form. In contrast, S100A9 relocalizes to the nucleus in an unphosphorylated form during...
2.
Lu E, Hara A, Sun S, Hallmark B, Snider J, Seeds M, et al.
Eur J Immunol . 2024 Apr; 54(6):e2350721. PMID: 38651231
Previous research suggests that group IIA-secreted phospholipase A (sPLA-IIA) plays a role in and predicts lethal COVID-19 disease. The current study reanalyzed a longitudinal proteomic data set to determine the...
3.
Long D, McCall C, Poole L
Redox Biol . 2023 Aug; 65:102841. PMID: 37566945
Lipopolysaccharide (LPS) is a known inducer of inflammatory signaling which triggers generation of reactive oxygen species (ROS) and cell death in responsive cells like THP-1 promonocytes and freshly isolated human...
4.
Stacpoole P, McCall C
Mitochondrion . 2023 Mar; 70:59-102. PMID: 36863425
Found in all organisms, pyruvate dehydrogenase complexes (PDC) are the keystones of prokaryotic and eukaryotic energy metabolism. In eukaryotic organisms these multi-component megacomplexes provide a crucial mechanistic link between cytoplasmic...
5.
Long D, McCall C, Poole L
bioRxiv . 2023 Feb; PMID: 36747682
Lipopolysaccharide (LPS) is a known inducer of inflammatory signaling which triggers generation of reactive oxygen species (ROS) and cell death in responsive cells like THP-1 promonocytes and freshly isolated human...
6.
Meyers A, Wang Z, Han W, Zhao Q, Zabalawi M, Duan L, et al.
Cell Rep . 2023 Jan; 42(1):111941. PMID: 36640341
Activating the macrophage NLRP3 inflammasome can promote excessive inflammation with severe cell and tissue damage and organ dysfunction. Here, we show that pharmacological or genetic inhibition of pyruvate dehydrogenase kinase...
7.
Lu E, Hara A, Sun S, Hallmark B, Snider J, Seeds M, et al.
medRxiv . 2022 Dec; PMID: 36451888
Previous research suggests that group IIA secreted phospholipase A (sPLA -IIA) plays a role in and predicts severe COVID-19 disease. The current study reanalyzed a longitudinal proteomic data set to...
8.
McCall C, Zhu X, Zabalawi M, Long D, Quinn M, Yoza B, et al.
J Leukoc Biol . 2022 Jul; 112(6):1509-1514. PMID: 35866365
Balancing high energy-consuming danger resistance and low energy supply of disease tolerance is a universal survival principle that often fails during sepsis. Our research supports the concept that sepsis phosphorylates...
9.
Oh T, Zabalawi M, Jain S, Long D, Stacpoole P, McCall C, et al.
JCI Insight . 2022 Jun; 7(12). PMID: 35730570
Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to an infection. The metabolic aberrations associated with sepsis underly an acute and organism-wide hyperinflammatory response and multiple organ...
10.
Dai J, Kumbhare A, Youssef D, Yao Z, McCall C, El Gazzar M
Mol Immunol . 2022 Jun; 150:246. PMID: 35717406
No abstract available.