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Matteo Ardini

Explore the profile of Matteo Ardini including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 284
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Recent Articles
1.
Ardini M, Aboagye S, Petukhova V, Kastrati I, Ippoliti R, Thatcher G, et al.
J Med Chem . 2024 Sep; 67(18):15947-15967. PMID: 39250602
Pyridine nucleotide-disulfide oxidoreductases are underexplored as drug targets, and thioredoxin reductases (TrxRs) stand out as compelling pharmacological targets. Selective TrxR inhibition is challenging primarily due to the reliance on covalent...
2.
Amodei L, Ruggieri A, Potenza F, Viele M, Dufrusine B, Franciotti R, et al.
J Transl Med . 2024 Aug; 22(1):787. PMID: 39180052
Background: Marinesco-Sjögren syndrome (MSS) is an autosomal recessive neuromuscular disorder that arises in early childhood and is characterized by congenital cataracts, myopathy associated with muscle weakness, and degeneration of Purkinje...
3.
Spizzichino S, Di Fonzo F, Marabelli C, Tramonti A, Chaves-Sanjuan A, Parroni A, et al.
Mol Cell . 2024 Jul; 84(14):2682-2697.e6. PMID: 38996576
RNA can directly control protein activity in a process called riboregulation; only a few mechanisms of riboregulation have been described in detail, none of which have been characterized on structural...
4.
Petukhova V, Aboagye S, Ardini M, Lullo R, Fata F, Byrne M, et al.
Nat Commun . 2023 Jun; 14(1):3737. PMID: 37349300
Only praziquantel is available for treating schistosomiasis, a disease affecting more than 200 million people. Praziquantel-resistant worms have been selected for in the lab and low cure rates from mass...
5.
Gabriele F, Palerma M, Ippoliti R, Angelucci F, Pitari G, Ardini M
Int J Mol Sci . 2023 May; 24(10). PMID: 37240041
Affibodies and designed ankyrin repeat proteins (DARPins) are synthetic proteins originally derived from the virulence factor protein A and the human ankyrin repeat proteins, respectively. The use of these molecules...
6.
Antonosante A, Castelli V, Sette M, Alfonsetti M, Catanesi M, Benedetti E, et al.
Biol Res . 2023 May; 56(1):27. PMID: 37226204
Background: The underlying mechanism of Parkinson's disease are still unidentified, but excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator activated receptors (PPARs) are transcription factors involved in the...
7.
Fata F, Gabriele F, Angelucci F, Ippoliti R, di Leandro L, Giansanti F, et al.
Sensors (Basel) . 2023 Jan; 23(2). PMID: 36679744
The demonstration of the first enzyme-based electrode to detect glucose, published in 1967 by S. J. Updike and G. P. Hicks, kicked off huge efforts in building sensors where biomolecules...
8.
Ardini M, Vago R, Fabbrini M, Ippoliti R
Toxins (Basel) . 2022 Sep; 14(9). PMID: 36136517
Suicide gene therapy is a relatively novel form of cancer therapy in which a gene coding for enzymes or protein toxins is delivered through targeting systems such as vesicles, nanoparticles,...
9.
Ardini M, Baiocco P, Di Matteo A, Giardina G, Miele A
Front Mol Biosci . 2022 Aug; 9:961452. PMID: 35911973
No abstract available.
10.
Bisauriya R, Antonaroli S, Ardini M, Angelucci F, Ricci A, Pizzoferrato R
Sensors (Basel) . 2022 Apr; 22(7). PMID: 35408102
In this study, nitrogen and sulfur co-doped carbon dots (NS-CDs) were investigated for the detection of heavy metals in water through absorption-based colorimetric response. NS-CDs were synthesized by a simple...