Luana di Leandro
Overview
Explore the profile of Luana di Leandro including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
96
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0
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Recent Articles
1.
di Leandro L, Colasante M, Pitari G, Ippoliti R
Toxins (Basel)
. 2023 Dec;
15(12).
PMID: 38133203
The production of therapeutic recombinant toxins requires careful host cell selection. Bacteria, yeast, and mammalian cells are common choices, but no universal solution exists. Achieving the delicate balance in toxin...
2.
Fata F, Gabriele F, Angelucci F, Ippoliti R, di Leandro L, Giansanti F, et al.
Sensors (Basel)
. 2023 Jan;
23(2).
PMID: 36679744
The demonstration of the first enzyme-based electrode to detect glucose, published in 1967 by S. J. Updike and G. P. Hicks, kicked off huge efforts in building sensors where biomolecules...
3.
Fortugno P, Monetta R, Cinquina V, Rigon C, Boaretto F, De Luca C, et al.
Eur J Hum Genet
. 2023 Jan;
31(5):596-601.
PMID: 36599937
Pathogenic variants in TGFBR1 are a common cause of Loeys-Dietz syndrome (LDS) characterized by life-threatening aortic and arterial disease. Generally, these are missense changes in highly conserved amino acids in...
4.
Fata F, Silvestri I, Ardini M, Ippoliti R, di Leandro L, Demitri N, et al.
ACS Infect Dis
. 2021 May;
7(7):1932-1944.
PMID: 33950676
Fragment screening is a powerful drug discovery approach particularly useful for enzymes difficult to inhibit selectively, such as the thiol/selenol-dependent thioredoxin reductases (TrxRs), which are essential and druggable in several...
5.
di Leandro L, Giansanti F, Mei S, Ponziani S, Colasante M, Ardini M, et al.
Front Pharmacol
. 2021 May;
12:588306.
PMID: 33935695
A novel suicide gene therapy approach was tested in U87 MG glioblastoma multiforme cells. A 26nt G-rich double-stranded DNA aptamer (AS1411) was integrated into a vector at the 5' of...
6.
Ardini M, Bellelli A, Williams D, di Leandro L, Giansanti F, Cimini A, et al.
Bioconjug Chem
. 2021 Jan;
32(1):43-62.
PMID: 33411522
Morpheeins are proteins that reversibly assemble into different oligomers, whose architectures are governed by conformational changes of the subunits. This property could be utilized in bionanotechnology where the building of...
7.
Dhez A, Benedetti E, Antonosante A, Panella G, Ranieri B, Florio T, et al.
J Cell Physiol
. 2017 Sep;
233(5):4091-4105.
PMID: 28941284
Targeted anticancer therapies demand discovery of new cellular targets to be exploited for the delivery of toxic molecules and drugs. In this perspective, in the last few years, nucleolin has...
8.
Ardini M, Golia G, Passaretti P, Cimini A, Pitari G, Giansanti F, et al.
Nanoscale
. 2016 Mar;
8(12):6739-53.
PMID: 26952635
Graphene oxide (GO) is rapidly emerging worldwide as a breakthrough precursor material for next-generation devices. However, this requires the transition of its two-dimensional layered structure into more accessible three-dimensional (3D)...
9.
Cristina P, Castagna M, Lombardi A, Barison E, Tagliabue G, Ceriotti A, et al.
Microb Cell Fact
. 2015 Apr;
14:19.
PMID: 25889802
Background: Antibodies raised against selected antigens over-expressed at the cell surface of malignant cells have been chemically conjugated to protein toxin domains to obtain immunotoxins (ITs) able to selectively kill...
10.
Ardini M, Giansanti F, di Leandro L, Pitari G, Cimini A, Ottaviano L, et al.
Nanoscale
. 2014 Jun;
6(14):8052-61.
PMID: 24910403
Nanomanipulation of matter to create responsive, ordered materials still remains extremely challenging. Supramolecular chemistry has inspired new strategies by which such nanomaterials can be synthesized step by step by exploiting...