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Matt J Neville

Explore the profile of Matt J Neville including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 5169
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Recent Articles
11.
Metz S, Krarup N, Bryrup T, Stoy J, Andersson E, Christoffersen C, et al.
J Endocr Soc . 2022 Apr; 6(5):bvac034. PMID: 35382499
Context: Blood lipid levels are linked to the risk of cardiovascular disease and regulated by genetic factors. A low-frequency polymorphism Arg82Cys (rs72836561) in the membrane protein nepmucin, encoded by ,...
12.
Ibi D, Boot M, Dolle M, Jukema J, Rosendaal F, Christodoulides C, et al.
J Lipid Res . 2022 Mar; 63(5):100193. PMID: 35278410
Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk of coronary artery disease (CAD). Genetic variation in the APOA5 gene encoding apolipoprotein A-V also...
13.
Graham S, Clarke S, Wu K, Kanoni S, Zajac G, Ramdas S, et al.
Nature . 2021 Dec; 600(7890):675-679. PMID: 34887591
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied prevalence worldwide owing to different dietary patterns and medication use. Despite advances in prevention and treatment, in...
14.
Hilton C, Vasan S, Neville M, Christodoulides C, Karpe F
Expert Rev Endocrinol Metab . 2021 Dec; 17(1):75-81. PMID: 34859739
Background: Body composition is associated with bone mineral density (BMD), but the precise associations between body fat distribution and BMD remain unclear. The regional adipose tissue depots have different metabolic...
15.
van Vliet N, Bos M, Thesing C, Chaker L, Pietzner M, Houtman E, et al.
BMC Med . 2021 Nov; 19(1):266. PMID: 34727949
Background: Observational studies suggest interconnections between thyroid status, metabolism, and risk of coronary artery disease (CAD), but causality remains to be proven. The present study aimed to investigate the potential...
16.
Chen J, Spracklen C, Marenne G, Varshney A, Corbin L, Luan J, et al.
Nat Genet . 2021 Jun; 53(6):840-860. PMID: 34059833
Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date, most genetic studies of glycemic traits have focused on individuals of European ancestry. Here...
17.
Ibi D, Blauw L, Noordam R, Dolle M, Jukema J, Rosendaal F, et al.
Atherosclerosis . 2021 May; 328:144-152. PMID: 34053745
Background And Aims: Mendelian randomization studies have shown that triglyceride (TG)- lowering lipoprotein lipase (LPL) alleles and low-density lipoprotein-cholesterol (LDL-C)-lowering alleles have independent beneficial associations on cardiovascular disease (CVD) risk....
18.
Bos M, Goulding N, Lee M, Hofman A, Bot M, Pool R, et al.
BMC Med . 2021 Mar; 19(1):69. PMID: 33731105
Background: Sleep traits are associated with cardiometabolic disease risk, with evidence from Mendelian randomization (MR) suggesting that insomnia symptoms and shorter sleep duration increase coronary artery disease risk. We combined...
19.
Surendran P, Feofanova E, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, et al.
Nat Genet . 2021 Mar; 53(5):762. PMID: 33727701
No abstract available.
20.
Surendran P, Feofanova E, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, et al.
Nat Genet . 2020 Nov; 52(12):1314-1332. PMID: 33230300
Genetic studies of blood pressure (BP) to date have mainly analyzed common variants (minor allele frequency > 0.05). In a meta-analysis of up to ~1.3 million participants, we discovered 106...