Anubha Mahajan
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Explore the profile of Anubha Mahajan including associated specialties, affiliations and a list of published articles.
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206
Citations
23644
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Recent Articles
1.
Benner C, Mahajan A, Anubha M, Pirinen M
PLoS Genet
. 2025 Jan;
21(1):e1011480.
PMID: 39787248
Recent statistical approaches have shown that the set of all available genetic variants explains considerably more phenotypic variance of complex traits and diseases than the individual variants that are robustly...
2.
Willems S, Ng N, Fernandez J, Fine R, Wheeler E, Wessel J, et al.
Wellcome Open Res
. 2024 Sep;
8():483.
PMID: 39280063
Background: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to...
3.
Ritchie S, Taylor H, Liang Y, Manikpurage H, Pennells L, Foguet C, et al.
medRxiv
. 2024 Sep;
PMID: 39228710
Combining information from multiple GWASs for a disease and its risk factors has proven a powerful approach for development of polygenic risk scores (PRSs). This may be particularly useful for...
4.
Verdiesen R, von Berg J, Said M, van der Harst P, Mahajan A, van Gils C, et al.
Rev Cardiovasc Med
. 2024 Jul;
23(8):269.
PMID: 39076620
Background: Higher age-specific circulating anti-Müllerian hormone (AMH) levels have been linked to a lower risk of cardiometabolic outcomes. However, whether AMH has a casual role in the etiology of these...
5.
Mandla R, Lorenz K, Yin X, Bocher O, Huerta-Chagoya A, Arruda A, et al.
medRxiv
. 2024 Jul;
PMID: 39072045
Discerning the mechanisms driving type 2 diabetes (T2D) pathophysiology from genome-wide association studies (GWAS) remains a challenge. To this end, we integrated omics information from 16 multi-tissue and multi-ancestry expression,...
6.
Bradfeld J, Kember R, Ulrich A, Balkhiyarova Z, Alyass A, Aris I, et al.
Genome Biol
. 2024 May;
25(1):129.
PMID: 38773652
No abstract available.
7.
Eriksen R, White M, Dawed A, Perez I, Posma J, Haid M, et al.
J Clin Endocrinol Metab
. 2024 Apr;
109(9):e1697-e1707.
PMID: 38686701
Context: The role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes (T2D) and obesity is not fully understood. Objective: We investigate the association of cardiometabolic, diet, and lifestyle parameters on...
8.
Shrine N, Guyatt A, Erzurumluoglu A, Jackson V, Hobbs B, Melbourne C, et al.
Nat Genet
. 2024 Apr;
56(5):1032-1033.
PMID: 38641645
No abstract available.
9.
Karjalainen M, Karthikeyan S, Oliver-Williams C, Sliz E, Allara E, Fung W, et al.
Nature
. 2024 Mar;
628(8006):130-138.
PMID: 38448586
Genome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism. This detailed knowledge of the genetic determinants of systemic metabolism has been...
10.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...