Caroline Hayward
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Explore the profile of Caroline Hayward including associated specialties, affiliations and a list of published articles.
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524
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52235
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Recent Articles
1.
Roselli C, Surakka I, S Olesen M, Sveinbjornsson G, Marston N, Choi S, et al.
Nat Genet
. 2025 Mar;
57(3):539-547.
PMID: 40050429
Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart failure and stroke. This large-scale meta-analysis of genome-wide association studies increased the power...
2.
de Bakker M, Welsh P, Sattar N, Lindahl B, Hammarsten O, Omland T, et al.
Clin Chem
. 2025 Feb;
PMID: 39969109
Background: Emerging evidence suggests that the ratio between cardiac troponin (cTn) I and T may provide information on the risk of adverse outcomes in individuals with cardiovascular disease. Whether the...
3.
Valo E, Richmond A, Mutter S, Dahlstrom E, Campbell A, Porteous D, et al.
Nat Commun
. 2025 Jan;
16(1):325.
PMID: 39746953
Dissecting the genetic mechanisms underlying urinary metabolite concentrations can provide molecular insights into kidney function and open possibilities for causal assessment of urinary metabolites with risk factors and disease outcomes....
4.
Allara E, Bell S, Smith R, Keene S, Gill D, Gaziano L, et al.
Commun Biol
. 2024 Dec;
7(1):1631.
PMID: 39643614
Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation...
5.
Roshandel D, Spiliopoulou A, McGurnaghan S, Iakovliev A, Lipschutz D, Hayward C, et al.
Diabetes
. 2024 Nov;
74(2):223-233.
PMID: 39556808
Identified genetic loci for C-peptide and type 1 diabetes (T1D) age at diagnosis (AAD) explain only a small proportion of their variation. We aimed to identify additional genetic loci associated...
6.
Major T, Takei R, Matsuo H, Leask M, Sumpter N, Topless R, et al.
Nat Genet
. 2024 Nov;
56(11):2577.
PMID: 39501129
No abstract available.
7.
Major T, Takei R, Matsuo H, Leask M, Sumpter N, Topless R, et al.
Nat Genet
. 2024 Oct;
56(11):2392-2406.
PMID: 39406924
Gout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular...
8.
Sidorenko J, Couvy-Duchesne B, Kemper K, Moen G, Bhatta L, Asvold B, et al.
Nat Genet
. 2024 Oct;
56(11):2352-2360.
PMID: 39375568
Linkage studies have successfully mapped loci underlying monogenic disorders, but mostly failed when applied to common diseases. Conversely, genome-wide association studies (GWASs) have identified replicable associations between thousands of SNPs...
9.
Willems S, Ng N, Fernandez J, Fine R, Wheeler E, Wessel J, et al.
Wellcome Open Res
. 2024 Sep;
8():483.
PMID: 39280063
Background: Genome-wide association studies for glycemic traits have identified hundreds of loci associated with these biomarkers of glucose homeostasis. Despite this success, the challenge remains to link variant associations to...
10.
Gadd D, Smith H, Mullin D, Chybowska O, Hillary R, Kimenai D, et al.
Clin Epigenetics
. 2024 Sep;
16(1):124.
PMID: 39256775
Background: Plasma growth differentiation factor 15 (GDF15) and N-terminal proB-type natriuretic peptide (NT-proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for GDF15 and NT-proBNP...