Mats Rudling
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Explore the profile of Mats Rudling including associated specialties, affiliations and a list of published articles.
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84
Citations
3957
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Recent Articles
1.
Voronova V, Sokolov V, Al-Khaifi A, Straniero S, Kumar C, Peskov K, et al.
Cell Mol Gastroenterol Hepatol
. 2020 Mar;
10(1):149-170.
PMID: 32112828
Background & Aims: Disturbances of the enterohepatic circulation of bile acids (BAs) are seen in a number of clinically important conditions, including metabolic disorders, hepatic impairment, diarrhea, and gallstone disease....
2.
Straniero S, Laskar A, Savva C, Hardfeldt J, Angelin B, Rudling M
J Lipid Res
. 2020 Feb;
61(4):480-491.
PMID: 32086245
Compared with humans, rodents have higher synthesis of cholesterol and bile acids (BAs) and faster clearance and lower levels of serum LDL-cholesterol. Paradoxically, they increase BA synthesis in response to...
3.
Johansson H, Edholm D, Kullberg J, Rosqvist F, Rudling M, Straniero S, et al.
Nutr Diabetes
. 2019 Nov;
9(1):34.
PMID: 31685793
Energy restriction reduces liver fat, improves hepatic insulin resistance and lipid metabolism. However, temporal data in which these metabolic improvements occur and their interplay is incomplete. By performing repeated MRI...
4.
Rosqvist F, Kullberg J, Stahlman M, Cedernaes J, Heurling K, Johansson H, et al.
J Clin Endocrinol Metab
. 2019 Aug;
104(12):6207-6219.
PMID: 31369090
Context: Saturated fatty acid (SFA) vs polyunsaturated fatty acid (PUFA) may promote nonalcoholic fatty liver disease by yet unclear mechanisms. Objective: To investigate if overeating SFA- and PUFA-enriched diets lead...
5.
Rudling M, Laskar A, Straniero S
J Lipid Res
. 2019 Jan;
60(3):498-505.
PMID: 30610083
Gallstone (GS) formation requires that bile is supersaturated with cholesterol, which is estimated by a cholesterol saturation index (CSI) calculated from gallbladder (GB) total lipids and the mol% (mole percent)...
6.
Ghosh M, Galman C, Rudling M, Angelin B
J Lipid Res
. 2018 Nov;
59(11):2253.
PMID: 30385517
No abstract available.
7.
An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers
Al-Khaifi A, Rudling M, Angelin B
Gastroenterology
. 2018 Jun;
155(4):1012-1016.
PMID: 29928896
Bile acid (BA) synthesis is regulated through suppression of hepatic cholesterol 7α-hydroxylase via farnesoid X receptor (FXR) activation in hepatocytes and/or enterocytes; in enterocytes, this process requires FGF19 signaling. To...
8.
Sjoberg B, Straniero S, Angelin B, Rudling M
Am J Physiol Endocrinol Metab
. 2017 May;
313(2):E167-E174.
PMID: 28487440
Bile acid (BA) production in mice is regulated by hepatic farnesoid X receptors and by intestinal fibroblast growth factor (FGF)-15 (in humans, FGF-19), a suppressor of BA synthesis that also...
9.
10.
Apro J, Tietge U, Dikkers A, Parini P, Angelin B, Rudling M
Arterioscler Thromb Vasc Biol
. 2016 Apr;
36(5):787-91.
PMID: 27034474
Objective: Patients with type 2 diabetes mellitus (T2D) have an increased risk of cardiovascular disease, the mechanism of which is incompletely understood. Their high-density lipoprotein (HDL) particles in plasma have...