Mats A Fernstrom
Overview
Explore the profile of Mats A Fernstrom including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
262
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0
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Recent Articles
1.
Lee S, Heinrich G, Fedorova L, Al-Share Q, Ledford K, Fernstrom M, et al.
Gastroenterology
. 2008 Oct;
135(6):2084-95.
PMID: 18848945
Background & Aims: Liver-specific inactivation of carcinoembryonic antigen-related cell adhesion molecule 1 causes hyperinsulinemia and insulin resistance, which result from impaired insulin clearance, in liver-specific S503A carcinoembryonic antigen-related cell adhesion...
2.
Najjar S, Yang Y, Fernstrom M, Lee S, DeAngelis A, Rjaily G, et al.
Cell Metab
. 2005 Aug;
2(1):43-53.
PMID: 16054098
Insulin is viewed as a positive regulator of fatty acid synthesis by increasing fatty acid synthase (FAS) mRNA transcription. We uncover a new mechanism by which insulin acutely reduces hepatic...
3.
Dai T, Abou-Rjaily G, Al-Share Q, Yang Y, Fernstrom M, DeAngelis A, et al.
J Biol Chem
. 2004 Aug;
279(43):45155-61.
PMID: 15316023
Inactivation of CEACAM1 in L-SACC1 mice by a dominant-negative transgene in liver impairs insulin clearance and increases serum free fatty acid (FFA) levels, resulting in insulin resistance. The contribution of...
4.
Poy M, Yang Y, Rezaei K, Fernstrom M, Lee A, Kido Y, et al.
Nat Genet
. 2002 Feb;
30(3):270-6.
PMID: 11850617
We hypothesized that insulin stimulates phosphorylation of CEACAM1 which in turn leads to upregulation of receptor-mediated insulin endocytosis and degradation in the hepatocyte. We have generated transgenic mice over-expressing in...
5.
Poy M, Ruch R, Fernstrom M, Okabayashi Y, Najjar S
J Biol Chem
. 2001 Nov;
277(2):1076-84.
PMID: 11694516
CEACAM1, a tumor suppressor (previously known as pp120), is a plasma membrane protein that undergoes phosphorylation on Tyr(488) in its cytoplasmic tail by the insulin receptor tyrosine kinase. Co-expression of...