Mathias Winterhalter
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Explore the profile of Mathias Winterhalter including associated specialties, affiliations and a list of published articles.
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3477
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Recent Articles
1.
Jiang R, Nilam M, Piselli C, Winterhalter M, Guo D, Yu S, et al.
Angew Chem Int Ed Engl
. 2025 Jan;
e202425157.
PMID: 39785152
Compartmentalized models with coupled catalytic networks are considered as "protocells" in the context of research related to the origin of life. To model the kinetics of a simple cellular uptake-metabolism...
2.
Vergalli J, Refregiers M, Ruggerone P, Winterhalter M, Pages J
Commun Biol
. 2024 Nov;
7(1):1508.
PMID: 39543341
The sophisticated envelope of Gram-negative bacteria modulates the uptake of small molecules in a side-chain-sensitive manner. Despite intensive theoretical and experimental investigations, a general set of pathways underpinning antibiotic uptake...
3.
Liu W, Zhu Q, Yang C, Fu Y, Zhang J, Li M, et al.
Nat Nanotechnol
. 2024 Aug;
19(11):1693-1701.
PMID: 39164412
Heteromeric pore-forming proteins often contain recognition patterns or stereospecific selection filters. However, the construction of heteromeric pore-forming proteins for single-molecule sensing is challenging due to the uncontrollability of producing position...
4.
Vikraman D, Majumdar B, Sk S, Weichbrodt C, Fertig N, Winterhalter M, et al.
Chem Sci
. 2024 Jun;
15(24):9333-9344.
PMID: 38903220
Bacterial membrane porins facilitate the translocation of small molecules while restricting large molecules, and this mechanism remains elusive at the molecular level. Here, we investigate the selective uptake of large...
5.
Bianchi M, Winterhalter M, Harbig T, Horompoli D, Ghai I, Nieselt K, et al.
ACS Infect Dis
. 2023 Dec;
10(1):127-137.
PMID: 38104323
The antibiotic fosfomycin (FOS) is widely recognized for the treatment of lower urinary tract infections with and has lately gained importance as a therapeutic option to combat multidrug-resistant bacteria. However,...
6.
Chen Y, Barba-Bon A, Gruner B, Winterhalter M, Aksoyoglu M, Pangeni S, et al.
J Am Chem Soc
. 2023 Jun;
145(24):13089-13098.
PMID: 37265356
Cobalt bisdicarbollides (COSANs) are inorganic boron-based anions that have been previously reported to permeate by themselves through lipid bilayer membranes, a propensity that is related to their superchaotropic character. We...
7.
Donoghue A, Winterhalter M, Gutsmann T
Membranes (Basel)
. 2023 May;
13(5).
PMID: 37233578
The effect of asymmetric membranes containing lipopolysaccharides (LPS) on the outer membrane protein F (OmpF) reconstitution, channel orientation, and antibiotic permeation across the outer membrane was investigated. After forming an...
8.
Miethke M, Pieroni M, Weber T, Bronstrup M, Hammann P, Halby L, et al.
Nat Rev Chem
. 2023 Apr;
5(10):726-749.
PMID: 37118182
An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to the current level of investment in...
9.
Milenkovic S, Wang J, Acosta-Gutierrez S, Winterhalter M, Ceccarelli M, Bodrenko I
Phys Chem Chem Phys
. 2023 Apr;
25(18):12712-12722.
PMID: 37098836
Transmembrane β-barrel proteins are key systems for transport phenomena in biology. Based on their broad substrate specificity, they represent good candidates for present and future technological applications, such as DNA/RNA...
10.
Long Y, Wanunu M, Winterhalter M
Chem Asian J
. 2023 Feb;
18(3):e202201253.
PMID: 36725362
This Special Collection highlights the most recent developments in nanopore electrochemistry and applications. In this Editorial, guest Editors Yi-Tao Long, Meni Wanunu, and Mathias Winterhalter briefly introduce the research published...