Massimo Masiero
Overview
Explore the profile of Massimo Masiero including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
610
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Recent Articles
1.
Sheldon H, Zhang W, Bridges E, Ang K, Lin S, Masiero M, et al.
J Extracell Biol
. 2024 Jun;
1(8):e52.
PMID: 38939053
ELTD1/ADGRL4 is an adhesion GPCR with an important role in angiogenesis. We recently identified a role for ELTD1 in wound repair and inflammation. Activation of ELTD1 in endothelial cells results...
2.
Masiero M, Boulos P, Crake C, Rowe C, Coviello C
Ultrasound Med Biol
. 2022 May;
48(8):1681-1690.
PMID: 35577660
Ultrasound-induced cavitation is currently under investigation for several potential applications in cancer treatment. Among these, the use of low-intensity ultrasound, coupled with the systemic administration of various cavitation nuclei, has...
3.
ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression
Sheldon H, Bridges E, Silva I, Masiero M, Favara D, Wang D, et al.
Mol Cancer Res
. 2021 Aug;
19(11):1957-1969.
PMID: 34348993
ELTD1/ADGRL4 expression is increased in the vasculature of a number of tumor types and this correlates with a good prognosis. Expression has also been reported in some tumor cells with...
4.
Bridges E, Sheldon H, Kleibeuker E, Ramberger E, Zois C, Barnard A, et al.
Angiogenesis
. 2020 Jun;
23(3):493-513.
PMID: 32506201
Angiogenesis, the formation of new blood vessels by endothelial cells, is a finely tuned process relying on the balance between promoting and repressing signalling pathways. Among these, Notch signalling is...
5.
Masiero M, Li D, Whiteman P, Bentley C, Greig J, Hassanali T, et al.
Mol Cancer Ther
. 2019 Aug;
18(11):2030-2042.
PMID: 31395687
The role of Notch signaling and its ligand JAGGED1 (JAG1) in tumor biology has been firmly established, making them appealing therapeutic targets for cancer treatment. Here, we report the development...
6.
Gu Y, Masiero M, Banham A
Oncotarget
. 2016 Mar;
7(20):29804-23.
PMID: 26934331
Notch is a highly conserved signaling system that allows neighboring cells to communicate, thereby controlling their differentiation, proliferation and apoptosis, with the outcome of its activation being highly dependent on...
7.
Minuzzo S, Agnusdei V, Pusceddu I, Pinazza M, Moserle L, Masiero M, et al.
Carcinogenesis
. 2014 Oct;
36(1):115-21.
PMID: 25355291
Activation of the NOTCH pathway occurs commonly in T acute lymphoblastic leukemia (T-ALL) mainly due to mutations in NOTCH1 or alterations in FBW7 and is involved in the regulation of...
8.
Li D, Masiero M, Banham A, Harris A
Front Oncol
. 2014 Oct;
4:254.
PMID: 25309874
The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence,...
9.
Snell C, Turley H, McIntyre A, Li D, Masiero M, Schofield C, et al.
PLoS One
. 2014 Feb;
9(2):e88955.
PMID: 24563687
The stabilisation of HIF-α is central to the transcriptional response of animals to hypoxia, regulating the expression of hundreds of genes including those involved in angiogenesis, metabolism and metastasis. HIF-α...
10.
Masiero M, Simoes F, Han H, Snell C, Peterkin T, Bridges E, et al.
Cancer Cell
. 2013 Jul;
24(2):229-41.
PMID: 23871637
Limited clinical benefits derived from anti-VEGF therapy have driven the identification of new targets involved in tumor angiogenesis. Here, we report an integrative meta-analysis to define the transcriptional program underlying...