Esther Bridges
Overview
Explore the profile of Esther Bridges including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
1131
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Recent Articles
1.
Yalaz C, Bridges E, Alham N, Zois C, Chen J, Bensaad K, et al.
Cancer Metab
. 2025 Jan;
13(1):4.
PMID: 39875986
No abstract available.
2.
Sheldon H, Zhang W, Bridges E, Ang K, Lin S, Masiero M, et al.
J Extracell Biol
. 2024 Jun;
1(8):e52.
PMID: 38939053
ELTD1/ADGRL4 is an adhesion GPCR with an important role in angiogenesis. We recently identified a role for ELTD1 in wound repair and inflammation. Activation of ELTD1 in endothelial cells results...
3.
Gupta T, Antanaviciute A, Hyun-Jung Lee C, Ottakandathil Babu R, Aulicino A, Christoforidou Z, et al.
Cancer Cell
. 2024 May;
42(5):797-814.e15.
PMID: 38744246
The success of checkpoint inhibitors (CPIs) for cancer has been tempered by immune-related adverse effects including colitis. CPI-induced colitis is hallmarked by expansion of resident mucosal IFNγ cytotoxic CD8 T ...
4.
Yalaz C, Bridges E, Alham N, Zois C, Chen J, Bensaad K, et al.
Cancer Metab
. 2024 Feb;
12(1):5.
PMID: 38350962
Background: PDE6H encodes PDE6γ', the inhibitory subunit of the cGMP-specific phosphodiesterase 6 in cone photoreceptors. Inhibition of PDE6, which has been widely studied for its role in light transduction, increases...
5.
GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner
Wang Z, Zhang N, Zhang M, Jiang Y, Ng A, Bridges E, et al.
Cancer Res
. 2023 Jul;
83(20):3400-3413.
PMID: 37463466
Significance: GTP cyclohydrolase functions as an oncogene in breast cancer and binds vimentin to induce epithelial-to-mesenchymal transition independently of its enzyme activity, which confers targetable vulnerabilities for developing breast cancer...
6.
Michl J, Monterisi S, White B, Blaszczak W, Hulikova A, Abdullayeva G, et al.
Cell Rep
. 2023 Jun;
42(6):112601.
PMID: 37270778
Acidic environments reduce the intracellular pH (pHi) of most cells to levels that are sub-optimal for growth and cellular functions. Yet, cancers maintain an alkaline cytoplasm despite low extracellular pH...
7.
Coupe N, Guo L, Bridges E, Campo L, Espinosa O, Colling R, et al.
Cell Oncol (Dordr)
. 2022 Dec;
46(2):391-407.
PMID: 36539575
Purpose: Despite recent advances, approximately 50% of patient with metastatic melanoma eventually succumb to the disease. Patients with melanomas harboring a BRAF mutation (BRAF) have a worse prognosis than those...
8.
Sacilotto N, Chouliaras K, Nikitenko L, Lu Y, Fritzsche M, Wallace M, et al.
Genes Dev
. 2022 Dec;
36(19-20):1096.
PMID: 36460466
No abstract available.
9.
Zois C, Hendriks A, Haider S, Pires E, Bridges E, Kalamida D, et al.
Cell Death Dis
. 2022 Jun;
13(6):573.
PMID: 35764612
Channelling of glucose via glycogen, known as the glycogen shunt, may play an important role in the metabolism of brain tumours, especially in hypoxic conditions. We aimed to dissect the...
10.
Westbrook R, Bridges E, Roberts J, Escribano-Gonzalez C, Eales K, Vettore L, et al.
Cell Rep
. 2022 Feb;
38(5):110320.
PMID: 35108535
The demands of cancer cell proliferation alongside an inadequate angiogenic response lead to insufficient oxygen availability in the tumor microenvironment. Within the mitochondria, oxygen is the major electron acceptor for...