Masayuki Fujinaga
Overview
Explore the profile of Masayuki Fujinaga including associated specialties, affiliations and a list of published articles.
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Articles
109
Citations
784
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Recent Articles
1.
Xie L, Zhang L, Hu K, Hanyu M, Zhang Y, Fujinaga M, et al.
Cell Rep Med
. 2025 Jan;
6(2):101945.
PMID: 39864439
No abstract available.
2.
Li Y, Mori W, Chaudhary A, Zhao C, Yamasaki T, Zhang Z, et al.
Eur J Med Chem
. 2025 Jan;
285:117246.
PMID: 39793441
Monoacylglycerol lipase (MAGL) is a 33 kDa cytosolic serine hydrolase that is widely distributed in the central nervous system and peripheral tissues. MAGL hydrolyzes monoacylglycerols into fatty acids and glycerol,...
3.
Li Y, Xiao Z, Mori W, Sun J, Yamasaki T, Rong J, et al.
Am J Nucl Med Mol Imaging
. 2024 Nov;
14(5):306-315.
PMID: 39583907
Metabotropic glutamate receptor 7 (mGlu) is a G protein-coupled receptor that is preferentially found in the active zone of neurotransmitter release in the central nervous system (CNS). mGlu plays a...
4.
Rong J, Yamasaki T, Chen J, Kumata K, Zhao C, Fujinaga M, et al.
ACS Omega
. 2024 Nov;
9(44):44154-44163.
PMID: 39524622
Phosphodiesterases (PDEs) constitute a superfamily of phosphohydrolytic enzymes that regulate intracellular second messenger signaling by hydrolyzing cyclic adenosine monophosphate and cyclic guanosine monophosphate. Among the 11 subfamilies of PDEs, phosphodiesterase...
5.
Yamasaki T, Mori W, Ohkubo T, Hiraishi A, Zhang Y, Kurihara Y, et al.
Brain Commun
. 2024 Jun;
6(3):fcae172.
PMID: 38863573
Intracellular pH is a valuable index for predicting neuronal damage and injury. However, no PET probe is currently available for monitoring intracellular pH . In this study, we developed a...
6.
Endo H, Ono M, Takado Y, Matsuoka K, Takahashi M, Tagai K, et al.
Neuron
. 2024 Jun;
112(15):2540-2557.e8.
PMID: 38843838
Deposition of α-synuclein fibrils is implicated in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), while in vivo detection of α-synuclein pathologies in these illnesses has been challenging. Here,...
7.
Rong J, Yamasaki T, Li Y, Kumata K, Zhao C, Haider A, et al.
ACS Med Chem Lett
. 2023 Oct;
14(10):1419-1426.
PMID: 37849554
Orexin 2 receptors (OXR) represent a vital subtype of orexin receptors intricately involved in the regulation of wakefulness, arousal, and sleep-wake cycles. Despite their importance, there are currently no positron...
8.
Hori Y, Nagai Y, Hori Y, Oyama K, Mimura K, Hirabayashi T, et al.
J Neurosci
. 2023 Aug;
43(39):6619-6627.
PMID: 37620158
Chemogenetic tools provide an opportunity to manipulate neuronal activity and behavior selectively and repeatedly in nonhuman primates (NHPs) with minimal invasiveness. Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are...
9.
Kawamura K, Yamasaki T, Fujinaga M, Kokufuta T, Zhang Y, Mori W, et al.
EJNMMI Radiopharm Chem
. 2023 Jul;
8(1):14.
PMID: 37458904
Background: A family of BF-chelated tetraaryl-azadipyrromethenes was developed as non-porphyrin photosensitizers for photodynamic therapy. Among the developed photosensitizers, ADPM06 exhibited excellent photochemical and photophysical properties. Molecular imaging is a useful...
10.
Xie L, Zhang L, Hu K, Hanyu M, Zhang Y, Fujinaga M, et al.
Cell Rep Med
. 2023 Apr;
4(4):100960.
PMID: 37003259
Metabotropic glutamate receptor 1 (mGluR1), a key mediator of glutamatergic signaling, is frequently overexpressed in tumor cells and is an attractive drug target for most cancers. Here, we present a...