Masayo Kotaka
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Explore the profile of Masayo Kotaka including associated specialties, affiliations and a list of published articles.
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28
Citations
611
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Recent Articles
1.
Li J, Wang L, Kotaka M, Lee M, Chan M
Toxins (Basel)
. 2022 Dec;
14(12).
PMID: 36548720
The crystal protein Cry5B, a pore-forming protein produced by the soil bacterium , has been demonstrated to have excellent anthelmintic activity. While a previous structure of the three-domain core region...
2.
Ting K, Leung C, Graeff R, Lee H, Hao Q, Kotaka M
Protein Sci
. 2015 Dec;
25(3):650-61.
PMID: 26660500
Cyclic ADP-ribose (cADPR) mobilizes intracellular Ca(2+) stores and activates Ca(2+) influx to regulate a wide range of physiological processes. It is one of the products produced from the catalysis of...
3.
Kwok J, Hui K, Lescar J, Kotaka M
Acta Crystallogr F Struct Biol Commun
. 2014 Mar;
70(Pt 2):248-51.
PMID: 24637767
The human innate immune system can detect invasion by microbial pathogens through pattern-recognition receptors that recognize structurally conserved pathogen-associated molecular patterns. Retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) are one...
4.
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer
Cheung Y, Kwok J, Law A, Watt R, Kotaka M, Tanner J
Proc Natl Acad Sci U S A
. 2013 Sep;
110(40):15967-72.
PMID: 24043813
DNA aptamers have significant potential as diagnostic and therapeutic agents, but the paucity of DNA aptamer-target structures limits understanding of their molecular binding mechanisms. Here, we report a distorted hairpin...
5.
Lam K, Lam W, Wong J, Chan L, Kotaka M, Ling T, et al.
Mol Microbiol
. 2013 Apr;
88(4):798-812.
PMID: 23614777
FliG and FliM are switch proteins that regulate the rotation and switching of the flagellar motor. Several assembly models for FliG and FliM have recently been proposed; however, it remains...
6.
Wang Y, Dutta S, Karlberg H, Devignot S, Weber F, Hao Q, et al.
J Virol
. 2012 Sep;
86(22):12294-303.
PMID: 22951837
Crimean-Congo hemorrhagic fever, a severe hemorrhagic disease found throughout Africa, Europe, and Asia, is caused by the tick-borne Crimean-Congo hemorrhagic fever virus (CCHFV). CCHFV is a negative-sense single-stranded RNA (ssRNA)...
7.
Chen M, Kotaka M, Vonrhein C, Bricogne G, Rao F, Chuah M, et al.
J Bacteriol
. 2012 Jul;
194(18):4837-46.
PMID: 22753070
The nucleotide messenger cyclic di-GMP (c-di-GMP) plays a central role in the regulation of motility, virulence, and biofilm formation in many pathogenic bacteria. EAL domain-containing phosphodiesterases are the major signaling...
8.
Law A, Lescar J, Hao Q, Kotaka M
Acta Crystallogr Sect F Struct Biol Cryst Commun
. 2012 Jun;
68(Pt 6):671-4.
PMID: 22684067
Adenylate kinases (AKs) are phosphotransferase enzymes that catalyze the interconversion of adenine nucleotides, thereby playing an important role in energy metabolism. In Plasmodium falciparum, three AK isoforms, namely PfAK1, PfAK2...
9.
Dutta S, Gupta G, Choi Y, Kotaka M, Fielding B, Song J, et al.
Biochem J
. 2012 May;
446(1):37-46.
PMID: 22640416
RNA helicases of the DEAD (Asp-Glu-Ala-Asp)-box family of proteins are involved in many aspects of RNA metabolism from transcription to RNA decay, but most of them have also been shown...
10.
Kotaka M, Graeff R, Chen Z, Zhang L, Lee H, Hao Q
J Mol Biol
. 2011 Dec;
415(3):514-26.
PMID: 22138343
Cyclic ADP-ribose (cADPR) is a calcium messenger that can mobilize intracellular Ca²⁺ stores and activate Ca²⁺ influx to regulate a wide range of physiological processes. Aplysia cyclase is the first...