Masato Nakafuku
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Explore the profile of Masato Nakafuku including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Azuma N, Tadokoro K, Yamada M, Nakafuku M, Nishina H
Int J Mol Sci
. 2025 Jan;
26(2.
PMID: 39859210
The eye primordium of vertebrates initially forms exactly at the side of the head. Later, the eyeball architecture is tuned to see ahead with better visual acuity, but its molecular...
2.
Shima Y, Sasagawa S, Ota N, Oyama R, Tanaka M, Kubota-Sakashita M, et al.
Sci Transl Med
. 2023 Jun;
15(700):eabq7721.
PMID: 37315111
Intracranial aneurysms (IAs) are a high-risk factor for life-threatening subarachnoid hemorrhage. Their etiology, however, remains mostly unknown at present. We conducted screening for sporadic somatic mutations in 65 IA tissues...
3.
Dong C, Zhao C, Chen X, Berry K, Wang J, Zhang F, et al.
J Neurosci
. 2022 Sep;
42(44):8373-8392.
PMID: 36127134
The chromatin remodeler CHD8 represents a high-confidence risk factor in autism, a multistage progressive neurologic disorder, however the underlying stage-specific functions remain elusive. In this study, by analyzing conditional knock-out...
4.
Del Aguila A, Adam M, Ullom K, Shaw N, Qin S, Ehrman J, et al.
Development
. 2022 Feb;
149(5).
PMID: 35132995
Distinct neural stem cells (NSCs) reside in different regions of the subventricular zone (SVZ) and generate multiple olfactory bulb (OB) interneuron subtypes in the adult brain. However, the molecular mechanisms...
5.
Salomone J, Qin S, Fufa T, Cain B, Farrow E, Guan B, et al.
Genes Dev
. 2020 Dec;
35(1-2):157-174.
PMID: 33334823
How homeodomain proteins gain sufficient specificity to control different cell fates has been a long-standing problem in developmental biology. The conserved Gsx homeodomain proteins regulate specific aspects of neural development...
6.
Roychoudhury K, Salomone J, Qin S, Cain B, Adam M, Potter S, et al.
Development
. 2020 Mar;
147(7).
PMID: 32122989
The Gsx2 homeodomain transcription factor promotes neural progenitor identity in the lateral ganglionic eminence (LGE), despite upregulating the neurogenic factor Ascl1. How this balance in maturation is maintained is unclear....
7.
Nakafuku M, Del Aguila A
Wiley Interdiscip Rev Dev Biol
. 2019 Dec;
9(3):e369.
PMID: 31825170
The mature mammalian brain has long been thought to be a structurally rigid, static organ since the era of Ramón y Cajal in the early 20th century. Evidence accumulated over...
8.
Chapman H, Riesenberg A, Ehrman L, Kohli V, Nardini D, Nakafuku M, et al.
Dev Biol
. 2018 Jul;
442(1):115-126.
PMID: 29990475
The homeobox gene Gsx2 has previously been shown to inhibit oligodendroglial specification in dorsal lateral ganglionic eminence (dLGE) progenitors of the ventral telencephalon. The precocious specification of oligodendrocyte progenitor cells...
9.
Qin S, Madhavan M, Waclaw R, Nakafuku M, Campbell K
Genesis
. 2016 Sep;
54(10):542-549.
PMID: 27618396
In this study, we generated a transgenic mouse line driving Cre and EGFP expression with two putative cis-regulatory modules (CRMs) (i.e., hs687 and hs678) upstream of the homeobox gene Gsx2...
10.
Gotz M, Nakafuku M, Petrik D
Cold Spring Harb Perspect Biol
. 2016 May;
8(7).
PMID: 27235475
Adult neurogenesis in the mammalian brain is often viewed as a continuation of neurogenesis at earlier, developmental stages. Here, we will critically review the extent to which this is the...