Masato Koike
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Explore the profile of Masato Koike including associated specialties, affiliations and a list of published articles.
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183
Citations
15596
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Recent Articles
1.
Sou Y, Yamaguchi J, Masuda K, Uchiyama Y, Maeda Y, Koike M
Life Sci Alliance
. 2024 Jul;
7(10).
PMID: 39079741
Protein glycosylation plays a vital role in various cellular functions, many of which occur within the Golgi apparatus. The Golgi pH regulator (GPHR) is essential for the proper functioning of...
2.
Koike M, Nojiri H, Kanazawa H, Sawa M, Miyagawa K, Yamaguchi H, et al.
Sci Rep
. 2024 May;
14(1):12093.
PMID: 38802533
Recently, we found significantly reduced total superoxide dismutase (SOD) activity in the cartilage of patients with end-stage knee osteoarthritis (OA). In this study, we aimed to evaluate the SOD activity...
3.
Tamagawa S, Sakai D, Nojiri H, Nakamura Y, Warita T, Matsushita E, et al.
Redox Biol
. 2024 Feb;
71:103091.
PMID: 38412803
Low back pain (LBP) is a pervasive global health concern, primarily associated with intervertebral disc (IVD) degeneration. Although oxidative stress has been shown to contribute to IVD degeneration, the underlying...
4.
Murakami Y, Umeshita S, Imanishi K, Yoshioka Y, Ninomiya A, Sunabori T, et al.
Mol Ther Methods Clin Dev
. 2024 Jan;
32(1):101176.
PMID: 38225934
Thirty genes are involved in the biosynthesis and modification of glycosylphosphatidylinositol (GPI)-anchored proteins, and defects in these genes cause inherited GPI deficiency (IGD). is X-linked and involved in the first...
5.
Uemura N, Marotta N, Ara J, Meymand E, Zhang B, Kameda H, et al.
Nat Commun
. 2023 Oct;
14(1):6892.
PMID: 37898614
Extraction of α-Synuclein (αSyn) aggregates from Lewy body disease (LBD) brains has been widely described yet templated fibrillization of LB-αSyn often fails to propagate its structural and functional properties. We...
6.
Yokota M, Yoshino Y, Hosoi M, Hashimoto R, Kakuta S, Shiga T, et al.
Front Cell Dev Biol
. 2023 Sep;
11:1171440.
PMID: 37745304
Endoplasmic reticulum-mitochondrial contact sites (ERMCS) play an important role in mitochondrial dynamics, calcium signaling, and autophagy. Disruption of the ERMCS has been linked to several neurodegenerative diseases, including Alzheimer's disease...
7.
Kanai A, Nishida Y, Iwamoto T, Yokota M, Aoyama S, Ueki K, et al.
Biochem Biophys Res Commun
. 2023 Jul;
676:132-140.
PMID: 37516030
Insulin is essential in controlling blood glucose levels, and its synthesis and secretion have been well investigated. In contrast, how insulin secretory granules (ISGs) are degraded in pancreatic beta cells...
8.
Leo S, Kato Y, Wu Y, Yokota M, Koike M, Yui S, et al.
Stem Cells
. 2023 May;
41(8):775-791.
PMID: 37228023
Cytochrome P450 3A4 (CYP3A4) is involved in first-pass metabolism in the small intestine and is heavily implicated in oral drug bioavailability and pharmacokinetics. We previously reported that vitamin D3 (VD3),...
9.
Kurusu R, Fujimoto Y, Morishita H, Noshiro D, Takada S, Yamano K, et al.
Dev Cell
. 2023 May;
58(13):1189-1205.e11.
PMID: 37192622
In addition to membranous organelles, autophagy selectively degrades biomolecular condensates, in particular p62/SQSTM1 bodies, to prevent diseases including cancer. Evidence is growing regarding the mechanisms by which autophagy degrades p62...
10.
Uemura N, Marotta N, Ara J, Meymand E, Zhang B, Kameda H, et al.
Res Sq
. 2023 Feb;
PMID: 36824782
Extraction of α-Synuclein (αSyn) aggregates from Lewy body disease (LBD) brains has been widely described yet templated fibrillization of LB-αSyn often fails to propagate its structural and functional properties. We...