Masaki Yagi
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Explore the profile of Masaki Yagi including associated specialties, affiliations and a list of published articles.
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16
Citations
250
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Recent Articles
1.
Fukushima T, Kristiansen T, Wong L, Keyes S, Tanaka Y, Mazzola M, et al.
bioRxiv
. 2025 Mar;
PMID: 40027782
Transitions between subsets of differentiating hematopoietic cells are widely regarded as unidirectional . Here, we introduce clonal phylogenetic tracer (CP-tracer) that sequentially introduces genetic barcodes, enabling high-resolution analysis of ~100,000...
2.
Yagi M, Horng J, Hochedlinger K
Development
. 2024 Sep;
151(19).
PMID: 39348466
Cellular plasticity progressively declines with development and differentiation, yet these processes can be experimentally reversed by reprogramming somatic cells to induced pluripotent stem cells (iPSCs) using defined transcription factors. Advances...
3.
Gorelov R, Weiner A, Huebner A, Yagi M, Haghani A, Brooke R, et al.
Stem Cell Reports
. 2024 Aug;
19(9):1242-1254.
PMID: 39178844
Epigenetic clocks, built on DNA methylation patterns of bulk tissues, are powerful age predictors, but their biological basis remains incompletely understood. Here, we conducted a comparative analysis of epigenetic age...
4.
Hoetker M, Yagi M, Di Stefano B, Langerman J, Cristea S, Wong L, et al.
Nat Cell Biol
. 2023 Jul;
25(8):1121-1134.
PMID: 37460697
The epigenetic mechanisms that maintain differentiated cell states remain incompletely understood. Here we employed histone mutants to uncover a crucial role for H3K36 methylation in the maintenance of cell identities...
5.
Yagi M, Okawa T, Kawano F
Data Brief
. 2021 Oct;
39:107474.
PMID: 34703860
CAD/CAM resin composite crowns are inexpensive tooth-colored prostheses that have been widely used. However, bonding between CAD/CAM resin composites and resin cements could be difficult since the resin composite is...
6.
Yagi M, Ji F, Charlton J, Cristea S, Messemer K, Horwitz N, et al.
Genes Dev
. 2021 Aug;
35(17-18):1209-1228.
PMID: 34413137
The generation of myotubes from fibroblasts upon forced MyoD expression is a classic example of transcription factor-induced reprogramming. We recently discovered that additional modulation of signaling pathways with small molecules...
7.
Yagi M, Kabata M, Tanaka A, Ukai T, Ohta S, Nakabayashi K, et al.
Nat Commun
. 2020 Jun;
11(1):3199.
PMID: 32581223
De novo establishment of DNA methylation is accomplished by DNMT3A and DNMT3B. Here, we analyze de novo DNA methylation in mouse embryonic fibroblasts (2i-MEFs) derived from DNA-hypomethylated 2i/L ES cells...
8.
Sakakura M, Ohta S, Yagi M, Tanaka A, Norihide J, Woltjen K, et al.
Biochem Biophys Res Commun
. 2019 Sep;
519(4):705-713.
PMID: 31543342
ES cell (ESC) identity is stably maintained through the coordinated regulation of transcription factors and chromatin structure. SMARCB1, also known as INI1, SNF5, BAF47, is one of the subunits of...
9.
Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, et al.
Stem Cell Reports
. 2019 May;
12(5):1113-1128.
PMID: 31056481
CpG islands (CGIs) including those at imprinting control regions (ICRs) are protected from de novo methylation in somatic cells. However, many cancers often exhibit CGI hypermethylation, implying that the machinery...
10.
Yagi M, Yamanaka S, Yamada Y
Lab Invest
. 2017 Sep;
97(10):1133-1141.
PMID: 28869587
In mammalian development, dynamic epigenetic reprogramming occurs in pre-implantation embryos and primordial germ cells and plays a critical role in conferring pluripotency on embryonic cells. Pluripotent stem cells, such as...