Masahito Watanabe
Overview
Explore the profile of Masahito Watanabe including associated specialties, affiliations and a list of published articles.
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105
Citations
1179
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Recent Articles
1.
Matsui K, Watanabe M, Yamamoto S, Kawagoe S, Ikeda T, Ohashi H, et al.
Nat Commun
. 2025 Mar;
16(1):2572.
PMID: 40089478
Fetal cell ablation models are crucial for studying congenital diseases, organ regeneration, and xenotransplantation. However, conventional knockout models offer limited control over disease severity, while conditional ablation models often require...
2.
Nagaya M, Uchikura A, Nakano K, Watanabe M, Matsunari H, Umeyama K, et al.
Regen Ther
. 2024 Sep;
26:783-791.
PMID: 39309395
Background: To overcome organ shortage during transplantation, interspecies organ generation via blastocyst complementation has been proposed, although not yet in evolutionarily distant species. To establish high levels of chimerism, low...
3.
Tsubota M, Watanabe M
Acta Crystallogr B Struct Sci Cryst Eng Mater
. 2024 Jul;
80(Pt 4):305-310.
PMID: 38958684
The synthesis of TaSe ring-shaped crystals displaying the coffee ring effect is investigated. By recrystallizing TaSe microcrystals dissolved in droplets of condensed Se gas, ring-shaped crystals were successfully grown. This...
4.
Okamoto K, Matsunari H, Nakano K, Umeyama K, Hasegawa K, Uchikura A, et al.
Regen Ther
. 2023 Sep;
24:451-458.
PMID: 37772130
Introduction: Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disorder caused by mutation in the dystrophin gene () on the X chromosome. Female DMD carriers occasionally exhibit symptoms such as...
5.
Watanabe M, Miyamoto H, Okamoto K, Nakano K, Matsunari H, Kazuki K, et al.
Mol Ther Nucleic Acids
. 2023 Aug;
33:444-453.
PMID: 37588685
Mammalian artificial chromosomes have enabled the introduction of extremely large amounts of genetic information into animal cells in an autonomously replicating, nonintegrating format. However, the evaluation of human artificial chromosomes...
6.
Kondo T, Inoue I, Umeyama K, Watanabe M, Matsunari H, Uchikura A, et al.
Lab Invest
. 2023 Apr;
103(2):100013.
PMID: 37039150
Amyotrophic lateral sclerosis (ALS) causes progressive degeneration of the motor neurons. In this study, we delivered the genetic construct including the whole locus of human mutant superoxide dismutase 1 (SOD1)...
7.
Watanabe M, Nagashima H
Methods Mol Biol
. 2023 Feb;
2637:269-292.
PMID: 36773154
Pigs have anatomical and physiological characteristics similar to humans; therefore, genetically modified pigs have the potential to become a valuable bioresource in biomedical research. In fact, considering the increasing need...
8.
Neyama D, Fakhruddin S, Inoue K, Kurita H, Osana S, Miyamoto N, et al.
Sens Actuators A Phys
. 2022 Nov;
349:114052.
PMID: 36447950
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been garnered increasing for its rapid worldwide spread. Each country had implemented city-wide lockdowns and immigration regulations to prevent the spread of...
9.
Fukui K, Takahashi T, Matsunari H, Uchikura A, Watanabe M, Nagashima H, et al.
J Inherit Metab Dis
. 2022 Jul;
45(6):1059-1069.
PMID: 35866457
Patients with urea cycle disorders intermittently develop episodes of decompensation with hyperammonemia. Although such an episode is often associated with starvation and catabolism, its molecular basis is not fully understood....
10.
Hasegawa K, Nakano K, Nagaya M, Watanabe M, Uchikura A, Matsunari H, et al.
Regen Ther
. 2022 Jun;
21:62-72.
PMID: 35765545
Introduction: Previously, we performed gene knockout (KO) of interleukin-2 receptor gamma () in porcine fetal fibroblasts using zinc finger nuclease-encoding mRNAs, subsequently generating KO pigs using these cells through somatic...